Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 10/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 10/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14252003 | 0.91 | LPAR1 (0.35) | LPAR1LPAR5 | |
| SCHEMBL14252009 | 0.88 | LPAR1 (0.41) | LPAR1LPAR5CHRM5CHRM1CHRM3 | |
| SCHEMBL4355002 | 0.88 | LPAR1 (0.42) | LPAR1LPAR5ALDH1A1KDM4EMITF | |
| SCHEMBL13632815 | 0.85 | LPAR1 (0.40) | LPAR1LPAR5ALDH1A1KDM4EMITF | |
| SCHEMBL13633128 | 0.79 | LPAR1 (0.42) | LPAR1LPAR5ALDH1A1KDM4EMITF | |
| SCHEMBL4366116 | 0.78 | LPAR1 (0.36) | LPAR1LPAR5 | |
| SCHEMBL4015362 | 0.76 | LPAR1 (0.43) | LPAR1LPAR5 | |
| SCHEMBL13632805 | 0.75 | LPAR1 (0.34) | LPAR1LPAR5 | |
| SCHEMBL4020149 | 0.75 | CARM1 (0.41) | ALDH1A1KDM4ES1PR1S1PR3MAPT | |
| SCHEMBL13638403 | 0.74 | LPAR1 (0.40) | LPAR1LPAR5ALDH1A1KDM4EMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008032156-A1 | DIARYL ETHER DERIVATIVES AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2008-03-20 | — | — | WO | disclosed |