Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466451 | 0.87 | CA12 (0.53) | SLC6A3SLC6A4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29733451 | 0.87 | CA12 (0.53) | SLC6A3SLC6A4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3139236 | 0.85 | CHEK1 (0.51) | SLC6A3SLC6A4ERN1KDM4ECYP1A2 | |
| SCHEMBL21798893 | 0.85 | KDM4E (0.54) | SLC6A3SLC6A4ERN1NPC1RAB9A | |
| SCHEMBL21857203 | 0.85 | ABL1 (0.59) | SLC6A3SLC6A4ERN1NPC1RAB9A | |
| SCHEMBL9813479 | 0.85 | CA12 (0.52) | SLC6A3SLC6A4ERN1NPC1RAB9A | |
| SCHEMBL4652494 | 0.81 | ERN1 (0.64) | ERN1NPC1RAB9ACASP3SENP7 | |
| SCHEMBL5192099 | 0.81 | ABCB1 (0.45) | ERN1 | |
| SCHEMBL16624241 | 0.81 | MKNK1 (0.44) | SLC6A3SLC6A4ERN1 | |
| SCHEMBL16624260 | 0.81 | TDP1 (0.56) | SLC6A3SLC6A4NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7339071-B2 | Aryl ethynyl phthalic acid derivative and method for producing the same | FUJIFILM CORPORATION (JP) | 2008-03-04 | — | — | US | disclosed |