SCHEMBL6466451

SCHEMBL6466451

COC(=O)c1ccc(-c2ccc(C(=O)OC)c(C(=O)OC)c2)cc1C(=O)OC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA7 P43166 2/20 0.53
CA9 Q16790 2/20 0.53
CA14 Q9ULX7 2/20 0.53
PDK2 Q15119 1/20 0.53
PDK4 Q16654 1/20 0.53
KDM4E B2RXH2 4/20 0.50
GAA P10253 3/20 0.50
GLA P06280 2/20 0.50
ALDH1A1 P00352 2/20 0.50
HSD17B10 Q99714 2/20 0.50
MAPT P10636 2/20 0.50
ATM Q13315 2/20 0.50
HPGD P15428 1/20 0.50
CASP1 P29466 1/20 0.50
CASP7 P55210 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29733451 1.00 CA12 (0.53) CA12CA1CA2CA7CA9
SCHEMBL9813479 0.98 CA12 (0.52) CA12CA1CA2CA7CA9
SCHEMBL9813482 0.92 NR4A2 (0.49) CA12CA1CA2CA7CA9
SCHEMBL1709647 0.90 CFD (0.47) CA12CA1CA2CA7CA9
SCHEMBL14252250 0.90 NR4A2 (0.59) KDM4EGAAALDH1A1MAPTHPGD
SCHEMBL70440 0.90 NR4A2 (0.59) KDM4EGAAALDH1A1MAPTHPGD
SCHEMBL6516527 0.90 CFD (0.47) CA12CA1CA2CA7CA9
SCHEMBL13941279 0.90 CFD (0.50) CA12CA1CA2CA7CA9
SCHEMBL338081 0.90 CFD (0.50) CA12CA1CA2CA7CA9
Water SCHEMBL15136858 0.89 CFD (0.46) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113667104-A Hyperbranched polyester and preparation method thereof 扬州帅帅高分子科技有限公司 2021-11-19 CN claimed
EP-0311374-B1 DICYLCOHEXYL-3,4,3'4'-TETRA-CARBOXYLIC ACID OR DIANHYDRIDE THEREOF AND POLYAMIDE-ACID AND POLYMIDE OBTAINED THEREFROM Hitachi Chemical Co., Ltd. (JP) 1992-09-09 EP claimed
US-4958001-A LIQUID CRYSTAL DISPLAY DEVICE HITACHI CHEMICAL COMPANY, LTD. (JP) 1990-09-18 US claimed
EP-0311374-A2 Dicylcohexyl-3,4,3'4'-tetra-carboxylic acid or dianhydride thereof and polyamide-acid and polymide obtained therefrom Hitachi Chemical Co., Ltd. (JP) 1989-04-12 EP claimed
JP-7215912-A None JP disclosed
CN-110818551-B Synthetic method of 3,3',4,4' -biphenyltetracarboxylic acid 常州市阳光药业有限公司 2022-06-24 CN disclosed
CN-113717136-A High-yield green safe synthesis method of 3,3',4,4' -biphenyl tetracarboxylic dianhydride 江西师范大学 2021-11-30 CN disclosed
CN-113667104-A Hyperbranched polyester and preparation method thereof 扬州帅帅高分子科技有限公司 2021-11-19 CN disclosed
CN-110818551-A Synthetic method of 3,3',4,4' -biphenyltetracarboxylic acid 常州市阳光药业有限公司 2020-02-21 CN disclosed
US-9469621-B2 Method for producing multisubstituted biphenyl compound and solid catalyst to be used therein KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-10-18 US disclosed
US-9469621-B2 Method for producing multisubstituted biphenyl compound and solid catalyst to be used therein KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-10-18 US disclosed
US-20150274689-A1 METHOD FOR PRODUCING MULTISUBSTITUTED BIPHENYL COMPOUND AND SOLID CATALYST TO BE USED THEREIN UBE CORPORATION (JP) 2015-10-01 US disclosed
EP-0311374-A2 Dicylcohexyl-3,4,3'4'-tetra-carboxylic acid or dianhydride thereof and polyamide-acid and polymide obtained therefrom Hitachi Chemical Co., Ltd. (JP) 1989-04-12 EP disclosed
US-4535105-A TETRACARBOXLYIC AROMATIC COMPOUND AND AROMATICDIAMINE UBE INDUSTRIES, LTD. (JP) 1985-08-13 US disclosed
EP-0019483-B1 METHOD OF PRODUCING BIPHENYLTETRACARBOXYLIC ESTERS UBE INDUSTRIES, LTD. (JP) 1982-09-29 EP disclosed
US-4338456-A PALLADIUM SALT CATALYST UBE INDUSTRIES, LTD. (JP) 1982-07-06 US disclosed
US-4294976-A DEHYDROGENATIVE DIMERIZATION IN THE PRESENCE OF OXALIC ACID AND A PALLADIUM CATALYST UBE INDUSTRIES, LTD. (JP) 1981-10-13 US disclosed
US-4292435-A PREFERENTIAL COUPLING OF THE PHENYL DIALKYL ESTER USING A CATALYST OF A PALLADIUM COMPOUND AND 1,10-PHENANTHROLINE UBE INDUSTRIES, LTD. (JP) 1981-09-29 US disclosed
EP-0019483-A1 Method of producing biphenyltetracarboxylic esters UBE INDUSTRIES, LTD. (JP) 1980-11-26 EP disclosed
US-3940426-A CRYSTALLIZATION OF ISOMERS UBE INDUSTRIES, LTD. (JA) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150274689-A1 METHOD FOR PRODUCING MULTISUBSTITUTED BIPHENYL COMPOUND AND SOLID CATALYST TO BE USED THEREIN DDT, CYP1A1, CYP1B1 CA12 1924/4885CA1 3481/4885CA2 4534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.