Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12751843 | 0.81 | SETD7 (0.40) | FNTAFNTBHPGDSETD7SIGMAR1 | |
| SCHEMBL12751865 | 0.80 | CYP2C9 (0.36) | FNTAFNTBNPC1RAB9ACYP2C9 | |
| SCHEMBL12751869 | 0.80 | CYP2C9 (0.36) | FNTAFNTBHPGDCYP2C9GAA | |
| SCHEMBL12751861 | 0.79 | SMN1; SMN2 (0.41) | FNTAFNTBHPGDNPC1RAB9A | |
| SCHEMBL12751856 | 0.79 | GAA (0.38) | HPGDRAB9ASMN1; SMN2CYP2C9SETD7 | |
| SCHEMBL1472667 | 0.79 | KDM4E (0.49) | — | |
| SCHEMBL12751846 | 0.77 | PTPN1 (0.39) | FNTAFNTBHPGDSETD7SIGMAR1 | |
| SCHEMBL12751022 | 0.74 | FNTA (0.40) | FNTAFNTBHPGDSETD7GAA | |
| SCHEMBL12751039 | 0.74 | FNTA (0.40) | FNTAFNTBHPGDSETD7GAA | |
| SCHEMBL12751836 | 0.72 | ALDH1A1 (0.39) | FNTAFNTBHPGDSETD7GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348337-B2 | Indole, azaindole and related heterocyclic 4-alkenyl piperidine amides | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-03-25 | — | — | US | disclosed |