SCHEMBL14255672

SCHEMBL14255672

CCCc1cccc(CN=C=O)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 2/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
GRIN2D O15399 2/20 0.37
GRIN3B O60391 2/20 0.37
GRIN1 Q05586 2/20 0.37
GRIN2A Q12879 2/20 0.37
GRIN2B Q13224 2/20 0.37
GRIN2C Q14957 2/20 0.37
GRIN3A Q8TCU5 2/20 0.37
SIGMAR1 Q99720 1/20 0.37
DRD2 P14416 2/20 0.37
DRD3 P35462 2/20 0.37
DRD1 P21728 1/20 0.37
DRD4 P21917 1/20 0.37
DRD5 P21918 1/20 0.37
CTSS P25774 1/20 0.36
CTSK P43235 1/20 0.36
ALOX5 P09917 1/20 0.36
CNR2 P34972 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26785 0.87 MIF (0.47) MIFMEN1KMT2AGRIN2DGRIN3B
SCHEMBL5465655 0.87 MIF (0.47) MIFMEN1KMT2AGRIN2DGRIN3B
SCHEMBL30317997 0.85 GABRA1 (0.41) MIFGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL1457268 0.85 GABRA1 (0.41) MIFGRIN2DGRIN3BGRIN1GRIN2A
Chloromethane SCHEMBL15655633 0.85 MIF (0.43) MIFMEN1KMT2AGRIN2DGRIN3B
SCHEMBL28048374 0.85 MIF (0.46) MIFMEN1KMT2AGRIN2DGRIN3B
SCHEMBL22471928 0.85 MIF (0.46) MIFMEN1KMT2AGRIN2DGRIN3B
Water SCHEMBL14972890 0.85 MIF (0.46) MIFMEN1KMT2AGRIN2DGRIN3B
SCHEMBL14015247 0.84 MIF (0.45) MIFMEN1KMT2AGRIN2DGRIN3B
SCHEMBL29263242 0.84 CYP19A1 (0.40) MIFMEN1KMT2AGRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4077485-A1 CROSSLINKABLE REACTIVE SILICONE ORGANIC COPOLYMERS DISPERSIONS Wacker Chemie AG (DE) 2022-10-26 EP claimed
WO-2021126174-A1 CROSSLINKABLE REACTIVE SILICONE ORGANIC COPOLYMERS DISPERSIONS WACKER CHEMIE AG (DE) 2021-06-24 WO claimed
EP-4077485-A1 CROSSLINKABLE REACTIVE SILICONE ORGANIC COPOLYMERS DISPERSIONS Wacker Chemie AG (DE) 2022-10-26 EP disclosed
WO-2021126174-A1 CROSSLINKABLE REACTIVE SILICONE ORGANIC COPOLYMERS DISPERSIONS WACKER CHEMIE AG (DE) 2021-06-24 WO disclosed
EP-1391296-B1 Presensitized lithographic plate comprising microcapsules FUJIFILM CORP (JP) 2008-03-26 EP disclosed