Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2636397 | 0.75 | MEN1 (0.60) | KDM4EHDAC8HDAC6HDAC1NOS3 | |
| SCHEMBL2636394 | 0.75 | MEN1 (0.60) | KDM4EHDAC8HDAC6HDAC1NOS3 | |
| SCHEMBL12812106 | 0.72 | HDAC8 (0.51) | KDM4EHDAC8HDAC6HDAC1KMT2A | |
| SCHEMBL13241449 | 0.71 | GRIN2B (0.46) | KDM4EMEN1KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL8506101 | 0.70 | HDAC8 (0.50) | HDAC8HDAC6HDAC1NOS3NOS1 | |
| Hydrochloric Acid SCHEMBL4986176 | 0.70 | HDAC8 (0.58) | KDM4EHDAC8HDAC6HDAC1KMT2A | |
| SCHEMBL10764944 | 0.68 | HDAC8 (0.50) | HDAC8HDAC6HDAC1NOS3NOS1 | |
| SCHEMBL507535 | 0.68 | HDAC8 (0.50) | HDAC8HDAC6HDAC1NOS3NOS1 | |
| SCHEMBL2744667 | 0.68 | HDAC8 (0.59) | KDM4EHDAC8HDAC6HDAC1KMT2A | |
| SCHEMBL8244021 | 0.67 | HDAC8 (0.53) | KDM4EHDAC8HDAC6HDAC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008025997-A1 | COMPOUNDS FOR USE IN OPTO-ELECTRICAL DEVICES | CDT OXFORD LIMITED (GB) | 2008-03-06 | — | — | WO | disclosed |