Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.81 |
| ▸ | CNR2 | P34972 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3305857 | 0.89 | CNR1 (1.00) | CNR1CNR2PARP1 | |
| SCHEMBL14258623 | 0.88 | CNR1 (0.83) | CNR1CNR2ALDH1A1SMN1; SMN2PARP1 | |
| SCHEMBL4781853 | 0.88 | CNR1 (0.70) | CNR1CNR2ALDH1A1PARP1 | |
| SCHEMBL14258913 | 0.88 | CNR1 (0.70) | CNR1CNR2ALDH1A1PARP1 | |
| SCHEMBL14258938 | 0.84 | CNR1 (0.66) | CNR1CNR2ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL14258617 | 0.84 | CNR1 (0.66) | CNR1CNR2ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL14258935 | 0.84 | CNR1 (0.63) | CNR1CNR2ALDH1A1PARP1 | |
| SCHEMBL14258909 | 0.84 | CNR1 (0.65) | CNR1CNR2ALDH1A1SMN1; SMN2PARP1 | |
| SCHEMBL14258604 | 0.84 | CNR1 (0.72) | CNR1CNR2ALDH1A1SMN1; SMN2PARP1 | |
| SCHEMBL13329597 | 0.82 | CNR1 (0.55) | CNR1CNR2ALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008036021-A1 | TETRAHYDRO-LH-PYRIDO [3,4 -B] INDOLE DERIVATIVES AS CBL RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2008-03-27 | — | — | WO | disclosed |