Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4083818 | 0.91 | DPP4 (0.75) | DPP4CHRM1 | |
| SCHEMBL14258907 | 0.88 | DPP4 (0.67) | DPP4CHRM1CYP3A4 | |
| SCHEMBL8353787 | 0.85 | DPP4 (0.81) | DPP4CHRM1CYP3A4 | |
| SCHEMBL8352407 | 0.84 | DPP4 (0.67) | DPP4CHRM1CYP3A4 | |
| SCHEMBL13912004 | 0.84 | DPP4 (0.67) | DPP4CHRM1CYP3A4 | |
| SCHEMBL8354369 | 0.84 | DPP4 (0.64) | DPP4CHRM1CYP3A4 | |
| SCHEMBL8353334 | 0.84 | DPP4 (0.67) | DPP4CHRM1CYP3A4 | |
| SCHEMBL13485016 | 0.84 | DPP4 (0.55) | DPP4CHRM1 | |
| SCHEMBL8351880 | 0.84 | DPP4 (0.55) | DPP4CHRM1 | |
| SCHEMBL13911728 | 0.84 | DPP4 (0.61) | DPP4CHRM1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641799-B1 | IMIDAZO-PYRIDAZINONE DERIVATIVES AND IMIDAZO-PYRIDONE DERIVATIVES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INT (DE) | 2008-03-12 | — | — | EP | disclosed |