SCHEMBL8353334

SCHEMBL8353334

CCn1c(N2CCC[C@@H](N)C2)nc2cnn(Cc3ccc(F)c4ccccc34)c(=O)c21

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 20/20 0.67
CHRM1 P11229 3/20 0.67
CYP3A4 P08684 4/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8352407 0.90 DPP4 (0.67) DPP4CHRM1CYP3A4
SCHEMBL13912004 0.90 DPP4 (0.67) DPP4CHRM1CYP3A4
Hydrochloric Acid SCHEMBL5843351 0.89 DPP4 (0.81) DPP4CHRM1
Hydrochloric Acid SCHEMBL5843341 0.89 DPP4 (0.81) DPP4CHRM1
SCHEMBL8353787 0.89 DPP4 (0.81) DPP4CHRM1CYP3A4
SCHEMBL8349850 0.89 DPP4 (0.83) DPP4CHRM1CYP3A4
SCHEMBL14258907 0.88 DPP4 (0.67) DPP4CHRM1CYP3A4
SCHEMBL8354369 0.87 DPP4 (0.64) DPP4CHRM1CYP3A4
SCHEMBL14259147 0.84 DPP4 (0.60) DPP4CHRM1CYP3A4
SCHEMBL13485028 0.84 DPP4 (0.64) DPP4CHRM1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004050658-A1 NOVEL SUBSTITUTED IMIDAZO-PYRIDINONES AND IMIDAZO-PYRIDAZEIONES, THE PRODUCTION AND USE THEREOF AS MEDICAMENTS BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2004-06-17 WO disclosed