Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8291533 | 1.00 | P2RX4 (0.55) | P2RX4ALDH1A1EPHX1LMNASERPINE1 | |
| SCHEMBL10205811 | 1.00 | P2RX4 (0.55) | P2RX4ALDH1A1EPHX1LMNASERPINE1 | |
| SCHEMBL16158123 | 1.00 | P2RX4 (0.55) | P2RX4ALDH1A1EPHX1LMNASERPINE1 | |
| SCHEMBL16316751 | 1.00 | P2RX4 (0.55) | P2RX4ALDH1A1EPHX1LMNASERPINE1 | |
| SCHEMBL3923672 | 0.87 | P2RX4 (0.55) | P2RX4ALDH1A1EPHX1LMNASERPINE1 | |
| SCHEMBL16518819 | 0.87 | P2RX4 (0.55) | P2RX4ALDH1A1EPHX1LMNASERPINE1 | |
| SCHEMBL17473729 | 0.87 | P2RX4 (0.55) | P2RX4ALDH1A1EPHX1LMNASERPINE1 | |
| SCHEMBL4612502 | 0.87 | P2RX4 (0.55) | P2RX4ALDH1A1EPHX1LMNASERPINE1 | |
| SCHEMBL5825056 | 0.87 | P2RX4 (0.55) | P2RX4ALDH1A1EPHX1LMNASERPINE1 | |
| SCHEMBL717418 | 0.87 | P2RX4 (0.55) | P2RX4ALDH1A1EPHX1LMNASERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008028057-A2 | SHIKIMIC ACID-DERIVED COMPOUNDS FOR INHIBITION AND DETECTION OF AURORA A-ASSOCIATED TUMORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-03-06 | — | — | WO | disclosed |