SCHEMBL1425965

SCHEMBL1425965

Oc1cccc(O)c1C=Cc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.63
TRPA1 O75762 1/20 0.61
NFE2L2 Q16236 3/20 0.56
BCHE P06276 1/20 0.47
MAPT P10636 1/20 0.47
CYP2C19 P33261 1/20 0.47
AHR P35869 1/20 0.47
ALOX5 P09917 1/20 0.47
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
MAOB P27338 4/20 0.46
PTPN1 P18031 1/20 0.46
HNF4A P41235 1/20 0.46
CYP19A1 P11511 2/20 0.45
MAOA P21397 2/20 0.45
TUBB1 Q9H4B7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1425963 1.00 TTR (0.63) TTRTRPA1NFE2L2BCHEMAPT
Acetic Acid SCHEMBL29022002 0.90 TTR (0.53) TTRTRPA1NFE2L2BCHEMAPT
SCHEMBL358118 0.87 TRPA1 (0.70) TTRTRPA1NFE2L2BCHEMAPT
SCHEMBL358117 0.87 TRPA1 (0.70) TTRTRPA1NFE2L2BCHEMAPT
SCHEMBL11748120 0.86 TTR (0.53) TTRTRPA1NFE2L2BCHEMAPT
(Z)-1,2-Diphenylethene SCHEMBL10658099 0.85 TRPA1 (0.73) TTRTRPA1NFE2L2BCHEMAPT
(Z)-1,2-Diphenylethene SCHEMBL10658094 0.85 TRPA1 (0.73) TTRTRPA1NFE2L2BCHEMAPT
Ethylene SCHEMBL10592531 0.84 TRPA1 (0.66) TTRTRPA1NFE2L2BCHEMAPT
Ethylene SCHEMBL10592522 0.84 TRPA1 (0.66) TTRTRPA1NFE2L2BCHEMAPT
SCHEMBL5003674 0.84 TTR (0.67) TTRTRPA1NFE2L2MAPTCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3589668-B1 NOVOLAC RESINS AND USE IN RUBBER COMPOSITIONS SUMITOMO CHEMICAL ADVANCED TECH LLC (US) 2025-06-04 EP claimed
US-11236190-B2 Novolac resins and use in rubber compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-02-01 US claimed
CN-112592448-A Mixed alkylresorcinol modified cardanol-formaldehyde adhesive resin, preparation method thereof, rubber composition and rubber product 北京彤程创展科技有限公司 2021-04-02 CN claimed
CN-112263502-A Application of phenethyl and styryl resorcinol glycoside compounds in anti-inflammatory and anti-aging skin care products 上海澄穆生物科技有限公司 2021-01-26 CN claimed
CN-112137908-A Application of phenethyl and styryl resorcinol glycoside compounds in melanin generation inhibitor 上海澄穆生物科技有限公司 2020-12-29 CN claimed
US-20200062884-A1 NOVOLAC RESINS AND USE IN RUBBER COMPOSITIONS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-02-27 US claimed
CN-110536912-A Novolac resin and the application in rubber composition SUMITOMO CHEMICAL ADVANCED TECH LLC D B A SUMIKA ELECTRONIC MATERIALS 2019-12-03 CN claimed
WO-2018160750-A1 NOVOLAC RESINS AND USE IN RUBBER COMPOSITIONS SUMITOMO CHEMICAL ADVANCED TECHNOLOGIES LLC, d.b.a. SUMIKA ELECTRONIC MATERIALS (US) 2018-09-07 WO claimed
CN-102316844-A COSMETIC METHOD FOR CONTROLLING BROWNING OF THE SKIN INDUCED BY UV RADIATION OREAL 2012-01-11 CN claimed
WO-2010078985-A2 COSMETIC METHOD FOR CONTROLLING BROWNING OF THE SKIN INDUCED BY UV RADIATION; COMPOSITIONS L'OREAL (FR) 2010-07-15 WO claimed
WO-2007077259-A1 SYNERGISTIC ACTIVE PREPARATIONS COMPRISING DIPHENYLMETHANE DERIVATIVES AND FURTHER SKIN AND/OR HAIR LIGHTENING AND/OR SENILE KERATOSIS REDUCING COMPOUNDS SYMRISE GMBH & CO. KG (DE) 2007-07-12 WO claimed
WO-2007077258-A1 STABILIZED PREPARATIONS COMPRISING PHENOLIC COMPOUNDS AND BENZOPHENONES SYMRISE GMBH & CO. KG (DE) 2007-07-12 WO claimed
US-20070098655-A1 Use of diphenylmethane derivatives as tyrosinase inhibitors SYMRISE AG (DE) 2007-05-03 US claimed
CN-1798550-A Use of diphenylmethane derivatives as tyrosinase inhibitors SYMRISE GMBH & CO KG (DE) 2006-07-05 CN claimed
CN-1784462-A Silane-modified phenolic resins and applications thereof INDSPEC CHEMICAL CORP (US) 2006-06-07 CN claimed
EP-1636307-A1 SILANE-MODIFIED PHENOLIC RESINS AND APPLICATIONS THEREOF INDSPEC CHEMICAL CORPORATION (US) 2006-03-22 EP claimed
US-20050154151-A1 Silane-modified phenolic resins and applications thereof INDSPEC CHEMICAL CORPORATION 2005-07-14 US claimed
US-6875807-B2 Silane-modified phenolic resins and applications thereof INDSPEC CHEMICAL CORPORATION (US) 2005-04-05 US claimed
WO-2004106427-A1 SILANE-MODIFIED PHENOLIC RESINS AND APPLICATIONS THEREOF INDSPEC CHEMICAL CORPORATION (US) 2004-12-09 WO claimed
US-20040241331-A1 Silane-modified phenolic resins and applications thereof INDSPEC CHEMICAL CORPORATION (US) 2004-12-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070098655-A1 Use of diphenylmethane derivatives as tyrosinase inhibitors TYR, DPM1, DDT TTR 790/4885TRPA1 1659/4885NFE2L2 539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.