Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.51 |
| ▸ | KLK7 | P49862 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PDE6D | O43924 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13713678 | 0.82 | KDM4E (0.48) | ALDH1A1KDM4EKLK7GAASMN1; SMN2 | |
| SCHEMBL14566671 | 0.77 | LMNA (0.45) | ALDH1A1KDM4EKLK7GAASMN1; SMN2 | |
| SCHEMBL18573907 | 0.77 | KDM4E (0.55) | ALDH1A1KDM4EKLK7GAASMN1; SMN2 | |
| SCHEMBL25121378 | 0.77 | LMNA (0.45) | ALDH1A1KDM4EKLK7GAASMN1; SMN2 | |
| SCHEMBL18573785 | 0.75 | KDM4E (0.54) | ALDH1A1KDM4EKLK7GAASMN1; SMN2 | |
| SCHEMBL14259788 | 0.71 | FFAR1 (0.46) | ALDH1A1HPGDKMT2AMEN1LMNA | |
| SCHEMBL14259790 | 0.68 | LMNA (0.36) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL13684839 | 0.67 | FFAR1 (0.45) | ALDH1A1HPGDKMT2AMEN1LMNA | |
| SCHEMBL4465439 | 0.67 | HPGD (0.59) | ALDH1A1KDM4ESMN1; SMN2HPGDKMT2A | |
| SCHEMBL6233047 | 0.67 | HPGD (0.59) | ALDH1A1KDM4ESMN1; SMN2HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064731-A1 | REMEDY FOR CHRONIC DISEASE | ONO PHARMACEUTICAL CO.,LTD. | 2008-03-13 | — | — | US | disclosed |
| US-7300917-B2 | Remedy for chronic disease | ONO PHARMACEUTICALS CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064731-A1 | REMEDY FOR CHRONIC DISEASE | EDNRA, EDNRB, LPAR2 | ALDH1A1 1978/4885KDM4E 2198/4885KLK7 1966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.