SCHEMBL142602

SCHEMBL142602

NCCSSCCC(=O)O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.72
THPO P40225 1/20 0.56
MAPT P10636 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
EHMT2 Q96KQ7 1/20 0.53
LMNA P02545 6/20 0.52
KMT2A Q03164 3/20 0.52
HSD17B10 Q99714 1/20 0.52
CYP1A2 P05177 2/20 0.50
THRB P10828 2/20 0.50
BLM P54132 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
GABRR1 P24046 2/20 0.50
GABRR3 A8MPY1 1/20 0.50
GABRP O00591 1/20 0.50
GABRD O14764 1/20 0.50
HDAC3 O15379 1/20 0.50
GABBR2 O75899 1/20 0.50
GABRA1 P14867 1/20 0.50
GABRB1 P18505 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1728032 0.97 TSHR (0.68) TSHRTHPOMAPTTDP1EHMT2
Cystamine SCHEMBL28779847 0.94 TSHR (0.63) TSHRTHPOMAPTTDP1EHMT2
Monoethanolamine SCHEMBL10477077 0.86 TSHR (0.68) TSHRTHPOTDP1LMNAKMT2A
Cystamine SCHEMBL8660518 0.86 TSHR (0.59) TSHRTHPOMAPTTDP1EHMT2
Cystamine SCHEMBL1133055 0.86 TSHR (0.59) TSHRTHPOMAPTTDP1EHMT2
Cystamine SCHEMBL31561460 0.85 HDAC3 (0.59) TSHRTHPOMAPTTDP1EHMT2
Cystamine SCHEMBL31561462 0.85 HDAC3 (0.59) TSHRTHPOMAPTTDP1EHMT2
Cystamine SCHEMBL9417963 0.85 TSHR (0.67) TSHRTHPOMAPTTDP1EHMT2
SCHEMBL95982 0.85 TSHR (1.00) TSHRTDP1LMNAKMT2AHSD17B10
Cystamine SCHEMBL445194 0.82 TSHR (0.62) TSHRTHPOMAPTTDP1EHMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109528690-B Double-response hollow mesoporous silicon-coated polydopamine grafted polyethylene glycol methacrylate drug-loaded microsphere and preparation method thereof 陕西师范大学 2020-10-16 CN claimed
US-9823245-B2 Nanodisc clathrates and uses thereof SOUTTER HOLLY (US) 2017-11-21 US claimed
EP-3083520-A1 NOVEL NANODISC CLATHRATES AND USES THEREOF DISCX LLC (US) 2016-10-26 EP claimed
US-20150177234-A1 NOVEL NANODISC CLATHRATES AND USES THEREOF SOUTTER HOLLY (US) 2015-06-25 US claimed
US-8968704-B2 Fluorescent labeling material and fluorescent labeling agent NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY (JP) 2015-03-03 US claimed
US-8906354-B2 Loaded latex optical molecular imaging probes containing lipophilic large stokes shift dyes BRUKER BIOSPIN CORPORATION (US) 2014-12-09 US claimed
EP-2343535-B1 FLUORESCENT LABELING MATERIAL AND FLUORESCENT LABELING AGENT NAT UNIV CORP SHIMANE UNIV (JP) 2013-09-25 EP claimed
CN-101421323-B Loaded latex optical molecular imaging probes CARESTREAM HEALTH INC 2013-03-13 CN claimed
EP-2433128-A1 CONJUGATE HAVING CLEAVABLE LINKING AGENT Abbott Laboratories (US) 2012-03-28 EP claimed
EP-2093194-B1 FLUORESCENT LABELING AGENT AND FLUORESCENT LABELING METHOD NAT UNIV CORP SHIMANE UNIV (JP) 2012-03-21 EP claimed
EP-2093194-A1 FLUORESCENT LABELING AGENT AND FLUORESCENT LABELING METHOD National University Corporation Shimane University (JP) 2009-08-26 EP claimed
WO-2009100002-A2 HIGHLY CONDUCTING SOLID STATE IONICS FOR ELECTROCHEMICAL SYSTEMS AND METHODS OF FABRICATING THEM USING LAYER-BY-LAYER TECHNOLOGY MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2009-08-13 WO claimed
CN-101421323-A Loaded latex optical molecular imaging probes CARESTREAM HEALTH INC (US) 2009-04-29 CN claimed
EP-2029357-A1 METHODS OF MAKING DECOMPOSABLE THIN FILMS OF POLYELECTROLYTES AND USES THEREOF Massachusetts Institute of Technology Inc. (US) 2009-03-04 EP claimed
EP-1886143-A1 BIOLOGICAL INDICATOR Steris, Inc. (US) 2008-02-13 EP claimed
WO-2007140402-A1 METHODS OF MAKING DECOMPOSABLE THIN FILMS OF POLYELECTROLYTES AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2007-12-06 WO claimed
WO-2007140391-A2 METHODS OF MAKING DECOMPOSABLE THIN FILMS OF POLYELECTROLYTES AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2007-12-06 WO claimed
WO-2007046865-A1 BIOLOGICAL INDICATOR STERIS, INC. (US) 2007-04-26 WO claimed
US-20070020469-A1 Methods of Making Decomposable Thin Films of Polyelectrolytes and Uses Thereof NATIONAL SCIENCE FOUNDATION 2007-01-25 US claimed
US-20060154259-A1 Diamond crystallites for biotechnological applications ACADEMIA SINICA (TW) 2006-07-13 US claimed