Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.66 |
| ▸ | NAT1 | P18440 | 5/20 | 0.66 |
| ▸ | MYC | P01106 | 4/20 | 0.66 |
| ▸ | MAX | P61244 | 3/20 | 0.66 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.66 |
| ▸ | CRHBP | P24387 | 2/20 | 0.65 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.65 |
| ▸ | CLK1 | P49759 | 1/20 | 0.65 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.65 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.65 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.65 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.65 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | IL1RN | P18510 | 1/20 | 0.61 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14226359 | 1.00 | ADAMTS5 (0.66) | ADAMTS5NAT1MYCMAXCISD1 | |
| SCHEMBL14151863 | 1.00 | ADAMTS5 (0.66) | ADAMTS5NAT1MYCMAXCISD1 | |
| SCHEMBL7969582 | 0.96 | NAT1 (0.70) | ADAMTS5NAT1MYCMAXCISD1 | |
| SCHEMBL7969587 | 0.96 | NAT1 (0.70) | ADAMTS5NAT1MYCMAXCISD1 | |
| SCHEMBL7974858 | 0.92 | ADAMTS5 (0.79) | ADAMTS5NAT1MYCMAXCISD1 | |
| SCHEMBL7968080 | 0.92 | ADAMTS5 (0.58) | ADAMTS5NAT1MYCMAXCISD1 | |
| SCHEMBL7974854 | 0.92 | ADAMTS5 (0.79) | ADAMTS5NAT1MYCMAXCISD1 | |
| SCHEMBL7972651 | 0.92 | ADAMTS5 (0.58) | ADAMTS5NAT1MYCMAXCISD1 | |
| SCHEMBL7972654 | 0.92 | ADAMTS5 (0.58) | ADAMTS5NAT1MYCMAXCISD1 | |
| SCHEMBL7968078 | 0.92 | ADAMTS5 (0.58) | ADAMTS5NAT1MYCMAXCISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7344850-B2 | Identification of active-site inhibitors of glycosyltransferases using a generalizable high-throughput screen | PRINCETON UNIVERSITY (US) | 2008-03-18 | — | — | US | disclosed |