Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.33 |
| ▸ | ITGAV | P06756 | 2/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 8/20 | 0.32 |
| ▸ | MC5R | P33032 | 8/20 | 0.32 |
| ▸ | MC3R | P41968 | 8/20 | 0.32 |
| ▸ | MC1R | Q01726 | 8/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.30 |
| ▸ | TSLP | Q969D9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14262567 | 0.90 | MC4R (0.34) | ITGB3ITGB1ITGAVITGA5MC4R | |
| SCHEMBL14262412 | 0.90 | ITGB3 (0.38) | ITGB3ITGB1ITGAVITGA5PDGFRB | |
| SCHEMBL14262503 | 0.88 | ITGB3 (0.34) | ITGB3ITGB1ITGAVITGA5PDGFRB | |
| SCHEMBL14075666 | 0.87 | ITGB3 (0.45) | ITGB3ITGB1ITGAVITGA5MC4R | |
| SCHEMBL14075694 | 0.87 | ITGB3 (0.45) | ITGB3ITGB1ITGAVITGA5MC4R | |
| SCHEMBL14262466 | 0.81 | MC4R (0.36) | ITGB3ITGB1ITGAVITGA5MC4R | |
| SCHEMBL14262415 | 0.81 | ITGB3 (0.39) | ITGB3ITGB1ITGAVITGA5PDGFRB | |
| SCHEMBL14262725 | 0.79 | ITGB3 (0.41) | ITGB3ITGB1ITGAVITGA5PDGFRB | |
| SCHEMBL14075690 | 0.78 | MC4R (0.42) | ITGB3ITGB1ITGAVITGA5MC4R | |
| SCHEMBL14075662 | 0.78 | MC4R (0.42) | ITGB3ITGB1ITGAVITGA5MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033557-A2 | CLICK CHEMISTRY-DERIVED CYCLIC PEPTIDOMIMETICS AS INTEGRIN MARKERS | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2008-03-20 | — | — | WO | disclosed |