Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | RXRB | P28702 | 1/20 | 0.51 |
| ▸ | SLC13A5 | Q86YT5 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14263159 | 0.85 | NQO1 (0.47) | FFAR1FFAR4KDM4EMAPTTDP1 | |
| SCHEMBL14274244 | 0.84 | RXRA (0.55) | RXRARXRBSLC13A5MAOBFDFT1 | |
| SCHEMBL14263158 | 0.78 | KCNH2 (0.44) | FDFT1FFAR1 | |
| SCHEMBL9260410 | 0.76 | RXRA (0.66) | RXRARXRBFGFR1FGFR2FGFR3 | |
| SCHEMBL29426410 | 0.76 | RXRA (0.66) | RXRARXRBFGFR1FGFR2FGFR3 | |
| SCHEMBL23419486 | 0.76 | RXRA (0.59) | RXRARXRBSLC13A5FGFR1FGFR2 | |
| SCHEMBL18314301 | 0.76 | RXRA (0.59) | RXRARXRBSLC13A5FGFR1FGFR2 | |
| SCHEMBL4759655 | 0.76 | RXRA (0.63) | RXRARXRBSLC13A5MAOBFGFR1 | |
| SCHEMBL4707626 | 0.76 | RXRA (0.59) | RXRARXRBSLC13A5MAOBFGFR1 | |
| SCHEMBL14263233 | 0.75 | TAAR1 (0.42) | MAOBTDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080064662-A1 | Methods and compositions for modulating sphingosine -1- phosphate (S1P) receptor activity | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2008-03-13 | — | — | US | disclosed |
| US-7241812-B2 | Methods and compositions for modulating sphingosine-1-phosphate (S1P) receptor activity | PRAECIS PHARMACEUTICALS, INC. (US) | 2007-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064662-A1 | Methods and compositions for modulating sphingosine -1- phosphate (S1P) receptor activity | S1PR1, S1PR2, S1PR3 | RXRA 1216/4885RXRB 934/4885SLC13A5 4650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.