Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 12/20 | 0.58 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | PI4KA | P42356 | 1/20 | 0.49 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.49 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL733947 | 0.90 | PIK3CD (0.59) | PIK3CDPIK3R1PIK3CGPIK3CBADORA2A | |
| SCHEMBL734302 | 0.83 | PIK3CD (0.57) | PIK3CDPIK3R1PIK3CGPIK3CBADORA2A | |
| SCHEMBL733295 | 0.83 | PIK3CD (0.57) | PIK3CDPIK3R1PIK3CGPIK3CBADORA2A | |
| SCHEMBL733067 | 0.82 | PIK3CD (0.60) | PIK3CDPIK3R1PIK3CGPIK3CBADORA2A | |
| SCHEMBL733839 | 0.81 | PIK3CD (0.75) | PIK3CDPIK3R1PIK3CGPIK3CBADORA2A | |
| SCHEMBL27897291 | 0.81 | PIK3CD (0.60) | PIK3CDPIK3R1PIK3CGPIK3CBADORA2A | |
| SCHEMBL733231 | 0.80 | PIK3CD (0.58) | PIK3CDPIK3R1PIK3CGPIK3CBADORA2A | |
| SCHEMBL732730 | 0.79 | PIK3CD (0.55) | PIK3CDPIK3R1PIK3CGPIK3CBADORA2A | |
| SCHEMBL733199 | 0.79 | PIK3CD (0.70) | PIK3CDPIK3R1PIK3CGPIK3CBADORA2A | |
| SCHEMBL734208 | 0.79 | PIK3CD (0.88) | PIK3CDPIK3R1PIK3CGPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1278748-B1 | INHIBITORS OF HUMAN PHOSPHATIDYL-INOSITOL 3-KINASE DELTA | ICOS CORP (US) | 2011-03-23 | — | — | EP | disclosed |