⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6442678 | 0.63 | — | — | |
| SCHEMBL2024929 | 0.63 | — | — | |
| SCHEMBL17675345 | 0.62 | — | — | |
| SCHEMBL610831 | 0.53 | — | — | |
| SCHEMBL423198 | 0.53 | — | — | |
| SCHEMBL246997 | 0.50 | MAPT (0.44) | — | |
| Methane SCHEMBL21489530 | 0.42 | CYP2A6 (0.89) | — | |
| SCHEMBL21518322 | 0.42 | — | — | |
| SCHEMBL9496102 | 0.42 | CYP2A6 (0.89) | — | |
| SCHEMBL15521433 | 0.40 | CYP2A6 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637454-B2 | Heterocyclic monoacylglycerol lipase (MAGL) inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2026-05-26 | — | — | US | disclosed |
| EP-4735430-A1 | MALT1 INHIBITORS | Janssen Pharmaceutica NV (BE) | 2026-05-06 | — | — | EP | disclosed |
| US-20250388536-A1 | 3-ALKYNYL CARBOXAMIDES AS AEP MODULATORS | HOFFMANN-LA ROCHE INC. (US) | 2025-12-25 | — | — | US | disclosed |
| EP-4652158-A1 | NOVEL PYRIMIDINYL SULFONAMIDE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-11-26 | — | — | EP | disclosed |
| US-20250346580-A1 | NOVEL PYRIMIDINYL SULFONAMIDE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2025-11-13 | — | — | US | disclosed |
| EP-4638436-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2025-10-29 | — | — | EP | disclosed |
| US-12454530-B2 | Amido cyclohexane acid derivatives as LPA receptor inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2025-10-28 | — | — | US | disclosed |
| EP-4634158-A2 | INHIBITORS OF PROCASPASE-6 ACTIVATION AND USES THEREOF | The Regents of University of California (US) | 2025-10-22 | — | — | EP | disclosed |
| US-12441718-B2 | Selective angiotensin II compounds | VICORE PHARMA AB (SE) | 2025-10-14 | — | — | US | disclosed |
| US-20250215012-A1 | IKZF2 DEGRADERS AND USES THEREOF | UNIV MICHIGAN (US) | 2025-07-03 | — | — | US | disclosed |
| US-20110071129-A1 | SPIRODIAMINE-DIARYL KETOXIME DERIVATIVE | MSD K.K. (JP) | 2011-03-24 | — | — | US | disclosed |
| CN-101553233-A | Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases | DECIPHERA PHARMACEUTICALS LLC (US) | 2009-10-07 | — | — | CN | disclosed |
| CN-1143962-A | Triazole compound and processes for preparation thereof | YUHAN CORP (KR) | 1997-02-26 | — | — | CN | disclosed |
| WO-1994021617-A1 | A PROCESS FOR PREPARING HALOGENATED ISOTHIAZOLES | DOWELANCO (US) | 1994-09-29 | — | — | WO | disclosed |
| CN-1019942-C | Sulfonamide compounds and salts thereof, herbicidal compositions containing them, and process for producing them | ISHIHARA SANGYO KAISHA (JP) | 1993-03-03 | — | — | CN | disclosed |
| EP-0234352-B1 | SULFONAMIDE COMPOUNDS AND SALTS THEREOF, HERBICIDAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR PRODUCING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1992-04-29 | — | — | EP | disclosed |
| US-4835282-A | Isothiazoles as intermediates for herbicidal sulfonamides | ISHIHARA SANGYO KAISHA LTD. (JP) | 1989-05-30 | — | — | US | disclosed |
| US-4790869-A | Sulfonamide compounds and salts thereof, herbicidal compositions containing them | ISHIHARA SANGYO KAISHA LTD. (JP) | 1988-12-13 | — | — | US | disclosed |
| CN-86100619-A | Power switching device | — | 1987-09-09 | — | — | CN | disclosed |
| EP-0234352-A1 | Sulfonamide compounds and salts thereof, herbicidal compositions containing them, and process for producing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-09-02 | — | — | EP | disclosed |