SCHEMBL246997

SCHEMBL246997

Brc1ccc(Br)c2nsnc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.44
KDM4E B2RXH2 3/20 0.44
MAPK1 P28482 2/20 0.44
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
ALDH1A1 P00352 2/20 0.37
POLB P06746 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
APAF1 O14727 1/20 0.37
THRB P10828 1/20 0.37
NR4A1 P22736 1/20 0.37
RECQL P46063 1/20 0.37
BLM P54132 1/20 0.37
PTPN11 Q06124 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HSD17B10 Q99714 2/20 0.36
HIF1A Q16665 1/20 0.36
NQO2 P16083 2/20 0.33
CCKBR P32239 1/20 0.32
TXNRD1 Q16881 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20428806 0.89 MAPT (0.40) MAPTKDM4EMAPK1KMT2AMEN1
Bicarbonate SCHEMBL30641166 0.83 MAPT (0.41) MAPTKDM4EMAPK1KMT2AMEN1
SCHEMBL1354892 0.80 MAPT (0.39) MAPTKDM4EMAPK1KMT2AMEN1
SCHEMBL23055925 0.78 MAPK1 (0.44) MAPTKDM4EMAPK1KMT2AMEN1
SCHEMBL28682479 0.77 KDM4E (0.34) MAPTKDM4EMAPK1
SCHEMBL29079180 0.77 MAPT (0.36) MAPTKDM4EMAPK1POLB
SCHEMBL29039768 0.77 KDM4E (0.37) MAPTKDM4EMAPK1POLB
SCHEMBL12136883 0.76 MAPT (0.33) MAPTKDM4EMAPK1KMT2AMEN1
SCHEMBL1396169 0.76 MAPT (0.35) MAPTKDM4EMAPK1KMT2AMEN1
SCHEMBL1354902 0.74 KDM4E (0.33) MAPTKDM4EMAPK1CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2091 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12636642-B2 Porphyrin-based metal coordination conjugated polymer, preparation method therefor, and application thereof in photocatalytic degradation of organic pollutants SOOCHOW UNIVERSITY (CN) 2026-05-26 US claimed
CN-119504649-B Benzothiadiazole type fluorescent probe for detecting HClO and preparation method thereof 西北师范大学 2026-05-12 CN claimed
US-20250212682-A1 FILM, PREPARATION METHOD THEREOF AND PHOTOELECTRIC DEVICE TCL TECHNOLOGY GROUP CORPORATION (CN) 2025-06-26 US claimed
CN-120078891-A Photodynamic targeted antibacterial microneedle patch and preparation method and application thereof 中南大学 2025-06-03 CN claimed
CN-120081801-A Tetracarboxylic acid organic ligand based on benzothiadiazole functional group for preparing metal organic framework, and preparation method and application thereof 江西理工大学 2025-06-03 CN claimed
CN-120058743-A Preparation method and application of novel fluorescent macrocyclic compound 吉林大学 2025-05-30 CN claimed
CN-120005135-A Acylhydrazone covalent organic framework material and preparation method and application thereof 东华大学 2025-05-16 CN claimed
CN-119978012-A Activatable bio-biomimetic probe with aggregation-induced emission and application 华中科技大学同济医学院附属协和医院 2025-05-13 CN claimed
CN-119931055-A Organic conjugated polymer containing benzothiadiazole unit, synthesis method and application 邢台学院 2025-05-06 CN claimed
CN-119912686-A D-A type imino conjugated microporous polymer catalyst for persulfate activation and preparation method and application thereof 东华大学 2025-05-02 CN claimed
US-20080033146-A1 METHODS FOR MANUFACTURING ARYL-ARYL COUPLED POLYMERS HEADWATERS NANOKINETIX, INC. (US) 2008-02-07 US claimed
WO-2008016956-A2 METHODS FOR MANUFACTURING ARY-ARYL COUPLED POLYMERS HEADWATERS TECHNOLOGY INNOVATION LLC (US) 2008-02-07 WO claimed
EP-1838752-A2 CATIONIC CONJUGATED POLYMERS SUITABLE FOR STRAND-SPECIFIC POLYNUCLEOTIDE DETECTION IN HOMOGENEOUS AND SOLID STATE ASSAYS The Regents of the University of California (US) 2007-10-03 EP claimed
US-7217824-B2 Process for preparing a 4,7-bis(5-halothien-2-yl)-2,1,3-benzothiadiazole and a precursor therefor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-15 US claimed
US-20060183140-A1 Cationic conjugated polymers suitable for strand-specific polynucleotide detection in homogeneous and solid state assays THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-08-17 US claimed
WO-2006074471-A2 CATIONIC CONJUGATED POLYMERS SUITABLE FOR STRAND-SPECIFIC POLYNUCLEOTIDE DETECTION IN HOMOGENEOUS AND SOLID STATE ASSAYS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-07-13 WO claimed
WO-2004103981-A1 PROCESS FOR PREPARING A 4,7-BIS(5-HALOTHIEN-2-YL)-2,1,3-BENZOTHIADIAZOLE AND A PRECURSOR THEREFOR DOW GLOBAL TECHNOLOGIES INC. (US) 2004-12-02 WO claimed
US-20040229925-A1 Process for preparing a 4,7-bis(5-halothien-2-yl)-2,1,3-benzothiadiazole and a precursor therefor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-18 US claimed
EP-1025142-B1 PROCESS FOR PREPARING CONJUGATED POLYMERS DOW GLOBAL TECHNOLOGIES INC (US) 2003-02-26 EP claimed
US-6362310-B1 LIGHT EMITTING POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-26 US claimed