Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.62 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.62 |
| ▸ | ACACA | Q13085 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | DHODH | Q02127 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.52 |
| ▸ | ACP1 | P24666 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14264128 | 0.89 | AURKA (0.62) | AURKAAURKBACACAMAPTTP53 | |
| SCHEMBL14264119 | 0.87 | ACACA (0.72) | AURKAAURKBACACAMAPTTP53 | |
| SCHEMBL14264126 | 0.86 | ACACA (0.71) | AURKAAURKBACACAMAPTTP53 | |
| SCHEMBL27986490 | 0.85 | ACACA (0.74) | AURKAAURKBACACAMAPTTP53 | |
| SCHEMBL21799200 | 0.85 | ACACA (0.74) | AURKAAURKBACACAMAPTTP53 | |
| SCHEMBL14264120 | 0.84 | ACACA (0.69) | AURKAAURKBACACAMAPTTP53 | |
| SCHEMBL14264122 | 0.82 | AURKA (0.62) | AURKAAURKBACACAMAPTTP53 | |
| SCHEMBL14264121 | 0.81 | AURKA (0.65) | AURKAAURKBACACAMAPTTP53 | |
| SCHEMBL14264127 | 0.81 | AURKA (0.63) | AURKAAURKBACACAMAPTTP53 | |
| SCHEMBL14264118 | 0.81 | AURKA (0.63) | AURKAAURKBACACAMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070086-A1 | Phase-Separated Polymer Electrolyte Membrane, Electrode - Phase-Separated Polymer Electrolyte Membrane Joint Using Same, Method for Manufacture Thereof, and Fuel Cell Using Same | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2008-03-20 | — | — | US | disclosed |
| US-20080070086-A1 | Phase-Separated Polymer Electrolyte Membrane, Electrode - Phase-Separated Polymer Electrolyte Membrane Joint Using Same, Method for Manufacture Thereof, and Fuel Cell Using Same | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2008-03-20 | — | — | US | disclosed |