Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30910314 | 0.83 | HSP90AA1 (0.44) | HSP90AA1NSD2G6PDCDK5CDK5R1 | |
| SCHEMBL14268587 | 0.82 | HSP90AA1 (0.38) | HSP90AA1NSD2G6PDCDK5CDK5R1 | |
| SCHEMBL14268588 | 0.79 | TDP1 (0.38) | HSP90AA1NSD2G6PDCDK5CDK5R1 | |
| SCHEMBL4857535 | 0.74 | HSP90AA1 (0.50) | HSP90AA1NSD2G6PDCDK5CDK5R1 | |
| SCHEMBL12387272 | 0.74 | TDP1 (0.41) | TDP1HDAC6MEN1ALDH1A1MAPT | |
| SCHEMBL15177510 | 0.71 | TDP1 (0.40) | HSP90AA1NSD2G6PDCDK5CDK5R1 | |
| SCHEMBL15177507 | 0.70 | TDP1 (0.38) | HSP90AA1NSD2G6PDCDK5CDK5R1 | |
| SCHEMBL14268589 | 0.70 | MEN1 (0.37) | HSP90AA1NSD2G6PDCDK5CDK5R1 | |
| SCHEMBL13236217 | 0.70 | HSP90AA1 (0.43) | HSP90AA1NSD2G6PDCDK5CDK5R1 | |
| SCHEMBL13533507 | 0.70 | HSP90AA1 (0.39) | HSP90AA1NSD2G6PDCDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329289-B2 | Use of triarylmethane derivatives as direct dyes in a dye composition, composition and implementation process | L'Oréal, S.A. (FR) | 2008-02-12 | — | — | US | disclosed |