Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14268589 | 0.92 | MEN1 (0.37) | TDP1HDAC6HSP90AA1NSD2G6PD | |
| SCHEMBL14268583 | 0.79 | HSP90AA1 (0.45) | TDP1HDAC6HSP90AA1NSD2G6PD | |
| SCHEMBL14268574 | 0.78 | THRB (0.39) | TDP1HDAC6SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14268587 | 0.76 | HSP90AA1 (0.38) | TDP1HDAC6HSP90AA1NSD2G6PD | |
| SCHEMBL30910314 | 0.74 | HSP90AA1 (0.44) | TDP1HDAC6HSP90AA1NSD2G6PD | |
| SCHEMBL15177503 | 0.72 | SMN1; SMN2 (0.39) | TDP1HDAC6HSP90AA1NSD2G6PD | |
| SCHEMBL15318100 | 0.70 | MEN1 (0.31) | TDP1HDAC6HSP90AA1NSD2G6PD | |
| SCHEMBL14607774 | 0.69 | THRB (0.35) | TDP1HDAC6SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14268573 | 0.67 | THRB (0.38) | TDP1HDAC6TLR9SMN1; SMN2MEN1 | |
| SCHEMBL4857535 | 0.67 | HSP90AA1 (0.50) | TDP1HDAC6HSP90AA1NSD2G6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329289-B2 | Use of triarylmethane derivatives as direct dyes in a dye composition, composition and implementation process | L'Oréal, S.A. (FR) | 2008-02-12 | — | — | US | disclosed |