Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C9 | P02748 | 3/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.80 |
| ▸ | MEN1 | O00255 | 3/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.80 |
| ▸ | APEX1 | P27695 | 2/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.80 |
| ▸ | BLM | P54132 | 2/20 | 0.80 |
| ▸ | CTH | P32929 | 2/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.80 |
| ▸ | POLB | P06746 | 2/20 | 0.80 |
| ▸ | MAPT | P10636 | 2/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.80 |
| ▸ | IKBKB | O14920 | 1/20 | 0.80 |
| ▸ | RGS12 | O14924 | 1/20 | 0.80 |
| ▸ | GMNN | O75496 | 1/20 | 0.80 |
| ▸ | USP2 | O75604 | 1/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aurintricarboxylic Acid SCHEMBL29353681 | 0.89 | MEN1 (1.00) | C9CYP1A2MEN1KMT2ACYP2D6 | |
| Aurintricarboxylic Acid SCHEMBL98495 | 0.89 | MEN1 (1.00) | C9CYP1A2MEN1KMT2ACYP2D6 | |
| Aurintricarboxylic Acid SCHEMBL29450069 | 0.89 | MEN1 (1.00) | C9CYP1A2MEN1KMT2ACYP2D6 | |
| Aurintricarboxylic Acid SCHEMBL29395768 | 0.88 | MEN1 (0.97) | C9CYP1A2MEN1KMT2ACYP2D6 | |
| Aurintricarboxylic Acid SCHEMBL515038 | 0.88 | MEN1 (0.97) | C9CYP1A2MEN1KMT2ACYP2D6 | |
| Aurintricarboxylic Acid SCHEMBL30831678 | 0.88 | MEN1 (0.97) | C9CYP1A2MEN1KMT2ACYP2D6 | |
| Aurintricarboxylic Acid SCHEMBL6158321 | 0.88 | MEN1 (0.97) | C9CYP1A2MEN1KMT2ACYP2D6 | |
| Aurintricarboxylic Acid SCHEMBL4644958 | 0.88 | MEN1 (0.97) | C9CYP1A2MEN1KMT2ACYP2D6 | |
| Aurintricarboxylic Acid SCHEMBL15874321 | 0.88 | MEN1 (0.97) | C9CYP1A2MEN1KMT2ACYP2D6 | |
| Aurintricarboxylic Acid SCHEMBL10791075 | 0.88 | MEN1 (0.97) | C9CYP1A2MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080076738-A1 | Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds | GILEAD SCIENCES, INC. | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076738-A1 | Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds | TYMP, PNP, PIKFYVE | C9 4073/4885CYP1A2 4127/4885MEN1 4347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.