Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4889898 | 0.86 | ALDH1A1 (0.46) | CFTRALDH1A1KDM4EPKMHPGD | |
| SCHEMBL21864798 | 0.75 | ALDH1A1 (0.42) | CFTRALDH1A1KDM4EPKMHPGD | |
| SCHEMBL14269607 | 0.73 | ALDH1A1 (0.37) | ALDH1A1PKMHPGDHSD17B10GAA | |
| SCHEMBL19145485 | 0.73 | ALDH1A1 (0.46) | CFTRALDH1A1KDM4EPKMHPGD | |
| SCHEMBL22359538 | 0.73 | ALDH1A1 (0.46) | CFTRALDH1A1KDM4EPKMHPGD | |
| SCHEMBL5106918 | 0.73 | ALDH1A1 (0.50) | CFTRALDH1A1KDM4EPKMHPGD | |
| SCHEMBL30996284 | 0.69 | ALDH1A1 (0.46) | CFTRALDH1A1KDM4EPKMHPGD | |
| SCHEMBL8120980 | 0.69 | ALDH1A1 (0.54) | CFTRALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8120979 | 0.69 | ALDH1A1 (0.54) | CFTRALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6170951 | 0.68 | CFTR (0.55) | CFTRALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080039625-A1 | Screening Methods | LAUTENS MARK | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039625-A1 | Screening Methods | CBR3, ZKSCAN2, CRBN | CFTR 3976/4885ALDH1A1 2175/4885KDM4E 3829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.