Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 12/20 | 0.54 |
| ▸ | NPC1 | O15118 | 10/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31227586 | 0.77 | JAK3 (0.48) | KDM4ERAB9ANPC1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31227240 | 0.76 | JAK3 (0.47) | KDM4ERAB9ANPC1MEN1KMT2A | |
| SCHEMBL239225 | 0.73 | POLB (0.67) | ALDH1A1RAB9ANPC1LMNAHTT | |
| SCHEMBL239226 | 0.73 | POLB (0.67) | ALDH1A1RAB9ANPC1LMNAHTT | |
| SCHEMBL1554136 | 0.72 | GSK3B (0.60) | KDM4ERAB9ANPC1LMNATP53 | |
| SCHEMBL17667093 | 0.71 | ALDH1A1 (1.00) | ALDH1A1KDM4ERAB9ANPC1LMNA | |
| SCHEMBL17667095 | 0.71 | ALDH1A1 (1.00) | ALDH1A1KDM4ERAB9ANPC1LMNA | |
| SCHEMBL14164232 | 0.71 | ALDH1A1 (0.71) | ALDH1A1KDM4ERAB9ANPC1LMNA | |
| Hydrochloric Acid SCHEMBL27395734 | 0.71 | GSK3B (0.58) | KDM4ERAB9ANPC1LMNATP53 | |
| SCHEMBL29542503 | 0.71 | DYRK1B (0.56) | RAB9ANPC1PKMPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031875-A1 | ADENOSINE DERIVATIVES AS A2A RECEPTOR AGONISTS | NOVARTIS AG (CH) | 2008-03-20 | — | — | WO | disclosed |