Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.34 |
| ▸ | HTR3A | P46098 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12727435 | 0.94 | P2RY12 (0.40) | P2RY12SMN1; SMN2GAANPC1TP53 | |
| SCHEMBL12768895 | 0.92 | P2RY12 (0.49) | P2RY12SMN1; SMN2GAANPC1TP53 | |
| SCHEMBL1639047 | 0.82 | P2RY12 (0.54) | P2RY12SMN1; SMN2GAANPC1TP53 | |
| SCHEMBL12727437 | 0.81 | P2RY12 (0.44) | P2RY12SMN1; SMN2GAANPC1TP53 | |
| SCHEMBL12727501 | 0.80 | P2RY12 (0.42) | P2RY12SMN1; SMN2GAANPC1TP53 | |
| SCHEMBL15624190 | 0.79 | P2RY12 (0.49) | P2RY12SMN1; SMN2GAANPC1TP53 | |
| SCHEMBL12727407 | 0.78 | P2RY12 (0.56) | P2RY12SMN1; SMN2GAANPC1TP53 | |
| SCHEMBL12768890 | 0.78 | P2RY12 (0.56) | P2RY12SMN1; SMN2GAATP53MAPT | |
| SCHEMBL12727503 | 0.78 | P2RY12 (0.42) | P2RY12SMN1; SMN2GAANPC1TP53 | |
| SCHEMBL1640668 | 0.77 | P2RY12 (0.56) | P2RY12SMN1; SMN2GAANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008036843-A2 | NITROGEN CONTAINING SUBSTITUTED HETEROCYCLES AS PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2008-03-27 | — | — | WO | disclosed |