Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HTR3A | P46098 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12768895 | 0.87 | P2RY12 (0.49) | P2RY12SMN1; SMN2GAANPC1RXFP1 | |
| SCHEMBL1639047 | 0.80 | P2RY12 (0.54) | P2RY12SMN1; SMN2GAANPC1RXFP1 | |
| SCHEMBL12727435 | 0.80 | P2RY12 (0.40) | P2RY12SMN1; SMN2GAANPC1RXFP1 | |
| SCHEMBL14273356 | 0.79 | P2RY12 (0.40) | P2RY12SMN1; SMN2GAANPC1RXFP1 | |
| SCHEMBL27756396 | 0.79 | P2RY12 (0.59) | P2RY12SMN1; SMN2GAANPC1RXFP1 | |
| SCHEMBL12727407 | 0.77 | P2RY12 (0.56) | P2RY12SMN1; SMN2GAANPC1RXFP1 | |
| SCHEMBL1640668 | 0.76 | P2RY12 (0.56) | P2RY12SMN1; SMN2GAANPC1RXFP1 | |
| SCHEMBL1640528 | 0.76 | P2RY12 (0.56) | P2RY12SMN1; SMN2GAANPC1RXFP1 | |
| SCHEMBL13074285 | 0.75 | P2RY12 (0.54) | P2RY12SMN1; SMN2GAANPC1RXFP1 | |
| SCHEMBL12768890 | 0.75 | P2RY12 (0.56) | P2RY12SMN1; SMN2GAARXFP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094272-B1 | NITROGEN CONTAINING SUBSTITUTED HETEROCYCLES AS PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARM INC (US) | 2014-03-26 | — | — | EP | disclosed |