Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1640705 | 0.91 | F10 (0.36) | F10F2KDM4EALDH1A1RXFP1 | |
| SCHEMBL12727585 | 0.89 | F10 (0.38) | F10F2 | |
| SCHEMBL1639115 | 0.87 | F10 (0.42) | F10F2 | |
| SCHEMBL1639790 | 0.87 | F10 (0.35) | F10F2KDM4EALDH1A1RXFP1 | |
| SCHEMBL1640301 | 0.87 | F10 (0.39) | F10F2KDM4ERXFP1 | |
| SCHEMBL1640628 | 0.87 | F10 (0.37) | F10KDM4EALDH1A1RXFP1 | |
| SCHEMBL14273475 | 0.84 | PYGL (0.34) | F10F2KDM4EALDH1A1RXFP1 | |
| SCHEMBL12727560 | 0.83 | F10 (0.37) | F10F2 | |
| SCHEMBL1640707 | 0.82 | F10 (0.36) | F10KDM4EALDH1A1RXFP1 | |
| SCHEMBL1639103 | 0.81 | EGFR (0.35) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008036843-A2 | NITROGEN CONTAINING SUBSTITUTED HETEROCYCLES AS PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2008-03-27 | — | — | WO | disclosed |