⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9169482 | 0.78 | — | — | |
| SCHEMBL24328029 | 0.78 | PKM (0.34) | — | |
| SCHEMBL876240 | 0.77 | — | — | |
| SCHEMBL166053 | 0.76 | FOLH1 (0.32) | — | |
| SCHEMBL1427724 | 0.74 | — | — | |
| SCHEMBL1428145 | 0.74 | — | — | |
| SCHEMBL253526 | 0.72 | — | — | |
| SCHEMBL6781632 | 0.70 | — | — | |
| SCHEMBL7008079 | 0.70 | — | — | |
| SCHEMBL446215 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101229164-B | Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives | BRISTOL MYERS SQUIBB CO | 2013-01-02 | — | — | CN | disclosed |
| EP-2300470-A2 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS GABA-A RECEPTOR MODULATORS | Sepracor Inc. (US) | 2011-03-30 | — | — | EP | disclosed |