Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.56 |
| ▸ | PAK4 | O96013 | 4/20 | 0.54 |
| ▸ | JAK2 | O60674 | 3/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14274434 | 0.87 | ADORA1 (0.56) | ADORA1ADORA3ADORA2AADORA2BPAK4 | |
| SCHEMBL4260180 | 0.87 | ADORA1 (0.75) | ADORA1ADORA3ADORA2AADORA2BPAK4 | |
| SCHEMBL4260177 | 0.87 | ADORA1 (0.75) | ADORA1ADORA3ADORA2AADORA2BPAK4 | |
| SCHEMBL14274541 | 0.87 | ADORA1 (0.74) | ADORA1ADORA3ADORA2AADORA2BPAK4 | |
| SCHEMBL14274343 | 0.78 | ADORA1 (0.58) | ADORA1ADORA2AMAP4K4IRAK4TP53 | |
| SCHEMBL4422705 | 0.75 | ADORA1 (0.77) | ADORA1ADORA3ADORA2AADORA2BPAK4 | |
| SCHEMBL4422702 | 0.75 | ADORA1 (0.77) | ADORA1ADORA3ADORA2AADORA2BPAK4 | |
| SCHEMBL4257018 | 0.74 | ADORA1 (0.75) | ADORA1ADORA3ADORA2AADORA2BPAK4 | |
| SCHEMBL13649809 | 0.74 | ADORA1 (0.75) | ADORA1ADORA3ADORA2AADORA2BPAK4 | |
| SCHEMBL4257021 | 0.74 | ADORA1 (0.75) | ADORA1ADORA3ADORA2AADORA2BPAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070936-A1 | Compounds specific to adenosine A1 receptors and uses thereof | OSI PHARMACEUTICALS, INC. | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070936-A1 | Compounds specific to adenosine A1 receptors and uses thereof | ADORA1, ADORA2A, ADORA3 | ADORA1 1/4885ADORA3 3/4885ADORA2A 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.