Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 17/20 | 0.76 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.52 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | STK4 | Q13043 | 1/20 | 0.45 |
| ▸ | STK3 | Q13188 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14276745 | 0.89 | SLC9A1 (0.61) | SLC9A1SLC9A2KIT | |
| SCHEMBL14276908 | 0.88 | SLC9A1 (0.74) | SLC9A1SLC9A2PDE10ASTK4STK3 | |
| SCHEMBL14276738 | 0.87 | SLC9A1 (1.00) | SLC9A1SLC9A2 | |
| SCHEMBL14276898 | 0.86 | SLC9A1 (0.75) | SLC9A1SLC9A2STK4STK3LRRK2 | |
| SCHEMBL14307261 | 0.86 | SLC9A1 (0.61) | SLC9A1SLC9A2 | |
| SCHEMBL14276901 | 0.84 | SLC9A1 (0.61) | SLC9A1SLC9A2 | |
| SCHEMBL14276900 | 0.83 | SLC9A1 (0.58) | SLC9A1SLC9A2KIT | |
| SCHEMBL14276743 | 0.81 | SLC9A1 (0.74) | SLC9A1SLC9A2 | |
| SCHEMBL14276744 | 0.80 | SLC9A1 (0.75) | SLC9A1SLC9A2 | |
| SCHEMBL14276735 | 0.77 | SLC9A1 (0.83) | SLC9A1SLC9A2KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326705-B2 | Heterocyclic sodium/proton exchange inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-02-05 | — | — | US | disclosed |
| US-7326705-B2 | Heterocyclic sodium/proton exchange inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-02-05 | — | — | US | disclosed |