SCHEMBL14276992

SCHEMBL14276992

CCc1cccc(/N=C/c2ccccc2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
GLA P06280 1/20 0.45
TP53 P04637 1/20 0.43
CA1 P00915 5/20 0.43
CA2 P00918 5/20 0.43
SIGMAR1 Q99720 8/20 0.42
CA9 Q16790 3/20 0.41
CA7 P43166 2/20 0.41
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GRIN1 Q05586 1/20 0.41
GRIN2A Q12879 1/20 0.41
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41
GRIN3A Q8TCU5 1/20 0.41
ACHE P22303 1/20 0.40
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11326750 0.81 CA1 (0.52) KDM4EALDH1A1L3MBTL1GLACA1
SCHEMBL11326747 0.81 CA1 (0.52) KDM4EALDH1A1L3MBTL1GLACA1
SCHEMBL11813342 0.81 CA1 (0.52) KDM4EALDH1A1L3MBTL1GLACA1
SCHEMBL11417698 0.80 CA1 (0.54) KDM4EALDH1A1L3MBTL1GLATP53
SCHEMBL11421201 0.80 ALDH1A1 (0.58) KDM4EALDH1A1L3MBTL1GLATP53
SCHEMBL11417699 0.80 CA1 (0.54) KDM4EALDH1A1L3MBTL1GLATP53
SCHEMBL11421203 0.80 ALDH1A1 (0.58) KDM4EALDH1A1L3MBTL1GLATP53
SCHEMBL14832385 0.79 CA1 (0.40) KDM4EALDH1A1L3MBTL1GLATP53
SCHEMBL14832384 0.79 CA1 (0.40) KDM4EALDH1A1L3MBTL1GLATP53
SCHEMBL20832384 0.78 MAPT (0.65) KDM4EALDH1A1CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7335673-B2 2,3-Diphenylpropionic acid derivatives or their salts, medicines or cell adhesion inhibitors containing the same, and their usage KAKEN PHARMACEUTICAL CO., LTD. (JP) 2008-02-26 US disclosed