Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916559 | 0.92 | SMN1; SMN2 (0.44) | ALOX15HPGDPOLBHTTSMN1; SMN2 | |
| SCHEMBL31079860 | 0.88 | ALOX15 (0.50) | ALOX15HPGDPOLBHTTMAPK1 | |
| SCHEMBL17979932 | 0.88 | ALOX15 (0.50) | ALOX15HPGDPOLBHTTMAPK1 | |
| SCHEMBL31557879 | 0.88 | HPGD (0.44) | ALOX15HPGDPOLBSMN1; SMN2MAPK1 | |
| SCHEMBL22123577 | 0.87 | SMN1; SMN2 (0.45) | ALOX15HPGDHTTSMN1; SMN2MAPK1 | |
| SCHEMBL24939964 | 0.86 | SMN1; SMN2 (0.44) | ALOX15HPGDHTTSMN1; SMN2MAPK1 | |
| SCHEMBL24870746 | 0.86 | SMN1; SMN2 (0.44) | ALOX15HPGDHTTSMN1; SMN2MAPK1 | |
| SCHEMBL24870886 | 0.86 | SMN1; SMN2 (0.44) | ALOX15HPGDHTTSMN1; SMN2MAPK1 | |
| SCHEMBL24916917 | 0.85 | SMN1; SMN2 (0.43) | ALOX15HPGDPOLBHTTSMN1; SMN2 | |
| SCHEMBL24916632 | 0.85 | SMN1; SMN2 (0.43) | ALOX15HPGDHTTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031594-A1 | BENZOXAZOLES AND OXAZOLOPYRIDINES BEING USEFUL AS JANUS KINASES INHIBITORS | NOVARTIS AG (CH) | 2008-03-20 | — | — | WO | disclosed |