SCHEMBL14280202

SCHEMBL14280202

CCC(C)(C)C(=O)OCCNC(=O)Sc1nc2ccccc2[nH]1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.45
SMN1; SMN2 Q16637 4/20 0.42
RAB9A P51151 3/20 0.42
NPC1 O15118 2/20 0.42
HIF1A Q16665 1/20 0.42
GAA P10253 1/20 0.41
BCHE P06276 1/20 0.41
KMT2A Q03164 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TXN P10599 2/20 0.41
MYC P01106 1/20 0.40
LMNA P02545 2/20 0.39
HPGD P15428 1/20 0.39
MPO P05164 1/20 0.39
RECQL P46063 1/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13399587 0.81 SMN1; SMN2 (0.47) POLBSMN1; SMN2RAB9ANPC1HIF1A
SCHEMBL13336619 0.80 LMNA (0.52) POLBSMN1; SMN2RAB9ANPC1BCHE
SCHEMBL13336535 0.79 BCHE (0.43) POLBSMN1; SMN2RAB9ANPC1HIF1A
SCHEMBL13336621 0.77 NPC1 (0.46) POLBSMN1; SMN2RAB9ANPC1KMT2A
SCHEMBL796388 0.74 SMN1; SMN2 (0.47) POLBSMN1; SMN2RAB9ANPC1HIF1A
SCHEMBL13336631 0.74 SMN1; SMN2 (0.51) POLBSMN1; SMN2RAB9ANPC1BCHE
SCHEMBL13125308 0.73 MEN1 (0.30) KMT2AMEN1
SCHEMBL12721827 0.73 SMN1; SMN2 (0.53) SMN1; SMN2RAB9ANPC1HIF1AGAA
SCHEMBL19047035 0.69 POLB (0.56) POLBSMN1; SMN2RAB9ANPC1GAA
SCHEMBL16125338 0.69 ASAH1 (0.60) POLBSMN1; SMN2GAAKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8551676-B2 Pigment-dispersed composition, curable composition, and color filter and production method thereof FUJIFILM CORPORATION (JP) 2013-10-08 US disclosed
US-20080026324-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD FOR PREPARATION OF LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2008-01-31 US disclosed