SCHEMBL14280205

SCHEMBL14280205

Cc1cc([Si](C)(O[Si](C)(c2ccccc2)c2ccc(N)c(C)c2)c2ccccc2)ccc1N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.39
TDP1 Q9NUW8 5/20 0.39
ALDH1A1 P00352 4/20 0.39
TSHR P16473 2/20 0.39
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
MAPT P10636 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
HTT P42858 1/20 0.36
S100B P04271 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
TP53 P04637 2/20 0.36
MAPK1 P28482 1/20 0.36
SKP2 Q13309 1/20 0.35
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
PKM P14618 1/20 0.35
HPGD P15428 1/20 0.33
ALOX12 P18054 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22151187 0.84 CYP3A4 (0.43) CYP3A4TDP1ALDH1A1TSHRNPC1
SCHEMBL3922330 0.77 CYP3A4 (0.48) CYP3A4TDP1ALDH1A1TSHRNPC1
SCHEMBL31410715 0.77 TSHR (0.42) CYP3A4TDP1ALDH1A1TSHRNPC1
SCHEMBL433139 0.77 ESR1 (0.42) ALDH1A1TSHRNPC1RAB9AMAPT
SCHEMBL22416498 0.73 CYP3A4 (0.52) CYP3A4TDP1ALDH1A1TSHRNPC1
SCHEMBL3929512 0.71 CYP3A4 (0.50) CYP3A4TDP1ALDH1A1TSHRNPC1
SCHEMBL14649181 0.71 ESR1 (0.38) MAPTESR1ESR2
SCHEMBL14981385 0.71 CYP3A4 (0.45) CYP3A4TDP1ALDH1A1TSHRNPC1
SCHEMBL15375372 0.70 CYP3A4 (0.48) CYP3A4TDP1ALDH1A1TSHRNPC1
SCHEMBL10338001 0.69 ESR1 (0.44) CYP3A4TDP1ALDH1A1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7320830-B2 Flame-retardant heat-resistant resin composition and adhesive film comprising the same HITACHI CHEMICAL CO., LTD. (JP) 2008-01-22 US disclosed