SCHEMBL15375372

SCHEMBL15375372

Cc1cc([Si](C)(c2ccc(N)c(C)c2)[Si](C)(C)C)ccc1N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 7/20 0.48
TDP1 Q9NUW8 7/20 0.48
ALDH1A1 P00352 5/20 0.48
TSHR P16473 3/20 0.48
S100B P04271 1/20 0.38
SKP2 Q13309 1/20 0.37
MAPK1 P28482 2/20 0.37
KDM4E B2RXH2 2/20 0.37
MAPT P10636 2/20 0.37
RAD52 P43351 2/20 0.37
THRB P10828 3/20 0.36
ALOX15 P16050 2/20 0.36
RECQL P46063 1/20 0.36
HIF1A Q16665 1/20 0.36
UHRF1 Q96T88 1/20 0.35
SMN1; SMN2 Q16637 4/20 0.34
TP53 P04637 3/20 0.34
TERT O14746 1/20 0.34
ESR1 P03372 2/20 0.34
AR P10275 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22416498 0.82 CYP3A4 (0.52) CYP3A4TDP1ALDH1A1TSHRS100B
SCHEMBL3929512 0.80 CYP3A4 (0.50) CYP3A4TDP1ALDH1A1TSHRS100B
SCHEMBL3922330 0.78 CYP3A4 (0.48) CYP3A4TDP1ALDH1A1TSHRS100B
SCHEMBL14981385 0.75 CYP3A4 (0.45) CYP3A4TDP1ALDH1A1TSHRS100B
SCHEMBL22151187 0.74 CYP3A4 (0.43) CYP3A4TDP1ALDH1A1TSHRS100B
SCHEMBL14280205 0.70 CYP3A4 (0.39) CYP3A4TDP1ALDH1A1TSHRS100B
SCHEMBL9426164 0.69 MAPT (0.44) CYP3A4TDP1ALDH1A1TSHRMAPK1
SCHEMBL15375289 0.67 CYP3A4 (0.48) CYP3A4TDP1ALDH1A1TSHRMAPK1
Orthotolidine SCHEMBL49414 0.66 CYP3A4 (1.00) CYP3A4TDP1ALDH1A1TSHRS100B
SCHEMBL33980 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2662378-B1 IMIDE COMPOUND, METHOD FOR PRODUCING SAME, THICKENING AGENT FOR GREASE, AND GREASE COMPOSITION JX NIPPON OIL & ENERGY CORP (JP) 2018-10-10 EP disclosed
US-9487726-B2 Imide compound, method for producing same, thickening agent for grease, and grease composition JX NIPPON OIL & ENERGY CORPORATION (JP) 2016-11-08 US disclosed
US-20130345102-A1 IMIDE COMPOUND, METHOD FOR PRODUCING SAME, THICKENING AGENT FOR GREASE, AND GREASE COMPOSITION JX NIPPON OIL & ENERGY CORPORATION (JP) 2013-12-26 US disclosed
EP-2662378-A1 IMIDE COMPOUND, METHOD FOR PRODUCING SAME, THICKENING AGENT FOR GREASE, AND GREASE COMPOSITION JX Nippon Oil & Energy Corporation (JP) 2013-11-13 EP disclosed