Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6500200 | 0.81 | ELANE (0.41) | TDP1ELANEKCNA3RAB9ANPC1 | |
| SCHEMBL17691839 | 0.77 | ERN1 (0.40) | ELANEKCNA3KLKB1MTNR1AMTNR1B | |
| SCHEMBL17231503 | 0.76 | ACLY (0.40) | KCNA3LMNAKLKB1MTNR1AMTNR1B | |
| SCHEMBL17231479 | 0.76 | ACLY (0.40) | KCNA3LMNAKLKB1MTNR1AMTNR1B | |
| SCHEMBL289180 | 0.74 | ELANE (0.56) | TDP1ELANEKCNA3RAB9ANPC1 | |
| SCHEMBL24155551 | 0.73 | NOTUM (0.45) | RAB9ANPC1NOTUMKDM4EALDH1A1 | |
| SCHEMBL1881874 | 0.72 | COMT (0.40) | TDP1RAB9ANPC1KMT2ANOTUM | |
| SCHEMBL17691865 | 0.72 | ERN1 (0.40) | RAB9ANPC1L3MBTL1LMNAKLKB1 | |
| SCHEMBL17691816 | 0.71 | ACLY (0.45) | KCNA3KLKB1ACLY | |
| SCHEMBL17231484 | 0.71 | ACLY (0.47) | KCNA3KLKB1ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031594-A1 | BENZOXAZOLES AND OXAZOLOPYRIDINES BEING USEFUL AS JANUS KINASES INHIBITORS | NOVARTIS AG (CH) | 2008-03-20 | — | — | WO | disclosed |