SCHEMBL14280244

SCHEMBL14280244

CC(C)(C)C1=CC(=CN=Nc2ccc(C#N)cc2)C=C(C(C)(C)C)C1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP19A1 P11511 1/20 0.36
▸ CYP1B1 Q16678 1/20 0.35
▸ BRD4 O60885 1/20 0.34
▸ KIF11 P52732 1/20 0.34
▸ NPC1 O15118 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ ATM Q13315 1/20 0.34
▸ GPR35 Q9HC97 1/20 0.34
▸ CA1 P00915 2/20 0.34
▸ CA2 P00918 2/20 0.34
▸ CA12 O43570 1/20 0.34
▸ CA9 Q16790 1/20 0.34
▸ NOS3 P29474 2/20 0.33
▸ NOS1 P29475 2/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ HTT P42858 1/20 0.33
▸ PPARD Q03181 2/20 0.33
▸ PPARA Q07869 2/20 0.33
▸ CA7 P43166 1/20 0.32
▸ GSK3B P49841 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18877782 0.92 BRD4 (0.34) CYP19A1CYP1B1BRD4KIF11NPC1
SCHEMBL13580310 0.84 ATM (0.38) NPC1KMT2AATMGPR35SMN1; SMN2
SCHEMBL14280269 0.83 NPC1 (0.37) NPC1KMT2AATMGPR35CA2
SCHEMBL13749169 0.83 ATM (0.37) NPC1KMT2AATMGPR35SMN1; SMN2
SCHEMBL13580484 0.82 ATM (0.36) NPC1KMT2AATMGPR35CA1
SCHEMBL15893569 0.82 CYP2D6 (0.36) CYP1B1NPC1KMT2AATMGPR35
SCHEMBL141575 0.82 ATM (0.36) NPC1KMT2AATMGPR35CA1
SCHEMBL13986178 0.82 ATM (0.36) NPC1KMT2AATMGPR35CA1
SCHEMBL15893570 0.82 NPC1 (0.36) BRD4NPC1KMT2AATMGPR35
SCHEMBL13986184 0.81 SMN1; SMN2 (0.40) NPC1KMT2AATMGPR35SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10782622-B2 Photoreceptor for electrophotography, method for manufacturing the same, and electrophotographic device FUJI ELECTRIC CO., LTD. (JP) 2020-09-22 — — US disclosed
US-10747129-B2 Electrophotographic photoconductor, method of manufacturing the same, and electrophotographic apparatus FUJI ELECTRIC CO., LTD. (JP) 2020-08-18 — — US disclosed
US-20190346780-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, METHOD OF MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD. (JP) 2019-11-14 — — US disclosed
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
US-7314692-B2 Phenylazomethylene-cyclohexadienone derivatives comprising electron withdrawing group and electrophotographic photoreceptor comprising the derivatives SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-01-01 — — US disclosed
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