SCHEMBL13986184

SCHEMBL13986184

CC(C)(C)C1=CC(=CN=Nc2ccccc2)C=C(C(C)(C)C)C1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ KMT2A Q03164 5/20 0.38
▸ ATM Q13315 4/20 0.38
▸ NPC1 O15118 2/20 0.38
▸ GPR35 Q9HC97 1/20 0.38
▸ POLB P06746 2/20 0.37
▸ GPR55 Q9Y2T6 1/20 0.37
▸ CYP2D6 P10635 1/20 0.34
▸ ALDH1A1 P00352 5/20 0.33
▸ MAPT P10636 7/20 0.33
▸ HPGD P15428 3/20 0.33
▸ NPSR1 Q6W5P4 2/20 0.33
▸ CES2 O00748 1/20 0.33
▸ PKM P14618 1/20 0.33
▸ CES1 P23141 1/20 0.33
▸ MPI P34949 1/20 0.33
▸ MEN1 O00255 3/20 0.31
▸ MAPK1 P28482 2/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ HSP90AA1 P07900 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21179846 1.00 SMN1; SMN2 (0.40) SMN1; SMN2KMT2AATMNPC1GPR35
SCHEMBL18877802 0.91 SMN1; SMN2 (0.34) SMN1; SMN2KMT2AATMNPC1GPR35
SCHEMBL13580310 0.88 ATM (0.38) SMN1; SMN2KMT2AATMNPC1GPR35
SCHEMBL14280269 0.86 NPC1 (0.37) SMN1; SMN2KMT2AATMNPC1GPR35
SCHEMBL13749169 0.86 ATM (0.37) SMN1; SMN2KMT2AATMNPC1GPR35
SCHEMBL13580408 0.85 NPC1 (0.37) SMN1; SMN2KMT2AATMNPC1GPR35
SCHEMBL141575 0.85 ATM (0.36) SMN1; SMN2KMT2AATMNPC1GPR35
SCHEMBL13986178 0.85 ATM (0.36) SMN1; SMN2KMT2AATMNPC1GPR35
SCHEMBL15893570 0.85 NPC1 (0.36) SMN1; SMN2KMT2AATMNPC1GPR35
SCHEMBL13580484 0.85 ATM (0.36) SMN1; SMN2KMT2AATMNPC1GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10782622-B2 Photoreceptor for electrophotography, method for manufacturing the same, and electrophotographic device FUJI ELECTRIC CO., LTD. (JP) 2020-09-22 — — US disclosed
US-10747129-B2 Electrophotographic photoconductor, method of manufacturing the same, and electrophotographic apparatus FUJI ELECTRIC CO., LTD. (JP) 2020-08-18 — — US disclosed
US-20190346780-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, METHOD OF MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD. (JP) 2019-11-14 — — US disclosed
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-9874824-B2 Electrophotographic photoreceptor and image formation device MITSUBISHI CHEMICAL CORPORATION (JP) 2018-01-23 — — US disclosed
US-9874824-B2 Electrophotographic photoreceptor and image formation device MITSUBISHI CHEMICAL CORPORATION (JP) 2018-01-23 — — US disclosed
US-20170371254-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMATION DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2017-12-28 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
US-20160011528-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMATION DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2016-01-14 — — US disclosed
US-20160011528-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMATION DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2016-01-14 — — US disclosed
US-7468230-B2 Wet-developing electrophotographic photoconductor and wet-developing image KYOCERA MITA CORPORATION (JP) 2008-12-23 — — US disclosed
US-20070009819-A1 Novel compound, and electrophotographic photoreceptor and electrophotographic apparatus made by using the same FUJI ELECTRIC DEVICE TECHNOLOGY CO., LTD (JP) 2007-01-11 — — US disclosed
US-20070009819-A1 Novel compound, and electrophotographic photoreceptor and electrophotographic apparatus made by using the same FUJI ELECTRIC DEVICE TECHNOLOGY CO., LTD (JP) 2007-01-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070009819-A1 Novel compound, and electrophotographic photoreceptor and electrophotographic apparatus made by using the same NR2E3, ALDH1A2, C3AR1 SMN1; SMN2 3005/4885KMT2A 2644/4885ATM 4310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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