Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14960144 | 0.78 | TDP1 (0.43) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL30489596 | 0.78 | TDP1 (0.36) | TDP1MEN1KMT2AGAAIDO1 | |
| SCHEMBL14280308 | 0.78 | TDP1 (0.47) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL18340829 | 0.74 | MEN1 (0.35) | TDP1MEN1KMT2AGAAIDO1 | |
| SCHEMBL16906203 | 0.74 | TDP1 (0.48) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL30112571 | 0.71 | TDP1 (0.51) | TDP1MEN1KMT2AGAAIDO1 | |
| SCHEMBL14280306 | 0.71 | TDP1 (0.37) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL30062131 | 0.71 | TDP1 (0.46) | TDP1MEN1KMT2AGAAIDO1 | |
| SCHEMBL22488117 | 0.70 | TDP1 (0.42) | TDP1MEN1KMT2AGAAIDO1 | |
| SCHEMBL14845755 | 0.70 | TDP1 (0.33) | TDP1MEN1KMT2AGAAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314959-B2 | Amino thiol compounds and compositions for use in conjunction with cancer therapy | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-01-01 | — | — | US | disclosed |
| US-7314959-B2 | Amino thiol compounds and compositions for use in conjunction with cancer therapy | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-01-01 | — | — | US | disclosed |