SCHEMBL14280360

SCHEMBL14280360

CC(=O)SCC(C)(C)CC(C)(C)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ACLY P53396 1/20 0.31
CYP2C19 P33261 2/20 0.31
TSHR P16473 2/20 0.31
ALDH1A1 P00352 1/20 0.31
ACACB O00763 1/20 0.31
ACACA Q13085 1/20 0.31
POLB P06746 1/20 0.30
BLM P54132 1/20 0.30
ATM Q13315 1/20 0.30
CYP2D6 P10635 1/20 0.30
HIF1A Q16665 1/20 0.30
CPB2 Q96IY4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7426792 0.84 TSHR (0.35) ACLYCYP2C19TSHRALDH1A1ACACB
SCHEMBL14296502 0.77 CYP2C19 (0.33) CYP2C19POLBBLMATM
SCHEMBL13212714 0.75 TSHR (0.44) CYP2C19TSHRALDH1A1POLBBLM
SCHEMBL20885267 0.75 CYP2C19 (0.34) CYP2C19POLBBLMATM
SCHEMBL14713463 0.75 CYP2C19 (0.34) CYP2C19ALDH1A1POLBBLMATM
SCHEMBL797973 0.72 TSHR (0.47) ACLYCYP2C19TSHRALDH1A1ACACB
SCHEMBL8359184 0.72 TSHR (0.36) ACLYCYP2C19TSHRALDH1A1ACACB
SCHEMBL9710090 0.72 TSHR (0.36) ACLYCYP2C19TSHRALDH1A1ACACB
SCHEMBL16863804 0.72 ACLY (0.40) ACLYCYP2C19TSHRALDH1A1ACACB
SCHEMBL7339999 0.71 TSHR (0.33) CYP2C19TSHRALDH1A1POLBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008028206-A2 METHOD FOR PRODUCING REACTIVE MONOLAYER UNITS Universität Linz (AT) 2008-03-13 WO disclosed