Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.56 |
| ▸ | PPARA | Q07869 | 9/20 | 0.56 |
| ▸ | PPARD | Q03181 | 2/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4871188 | 0.98 | PPARD (0.57) | PPARGPPARAPPARDHRH3 | |
| SCHEMBL4873102 | 0.93 | PPARG (0.52) | PPARGPPARAPPARDHRH3 | |
| SCHEMBL4872350 | 0.92 | PPARG (0.55) | PPARGPPARAPPARDHRH3 | |
| SCHEMBL4866992 | 0.85 | HRH3 (0.54) | PPARGPPARAPPARDHRH3 | |
| SCHEMBL4873144 | 0.85 | PPARG (0.54) | PPARGPPARAPPARDHRH3 | |
| SCHEMBL4866928 | 0.80 | PPARA (0.51) | PPARGPPARAPPARDHRH3 | |
| SCHEMBL4863686 | 0.78 | HRH3 (0.69) | PPARGHRH3 | |
| SCHEMBL4870642 | 0.75 | PPARD (0.58) | PPARGPPARAPPARD | |
| SCHEMBL2521542 | 0.72 | PPARG (0.57) | PPARGPPARAPPARD | |
| SCHEMBL2521544 | 0.72 | PPARG (0.57) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7319170-B2 | N-cyclohexylaminocarbonyl benzensulfonmide derivatives | MERCK & CO., INC. (US) | 2008-01-15 | — | — | US | disclosed |
| US-7319170-B2 | N-cyclohexylaminocarbonyl benzensulfonmide derivatives | MERCK & CO., INC. (US) | 2008-01-15 | — | — | US | disclosed |