Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 14/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 14/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 14/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 14/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 14/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 14/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14315154 | 0.90 | PSEN1 (0.51) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14280402 | 0.78 | KDM4E (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14160816 | 0.78 | DYRK1A (0.57) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14280397 | 0.77 | PSEN1 (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14160813 | 0.74 | KDM4E (0.57) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14160792 | 0.73 | PSEN1 (0.57) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14315155 | 0.71 | KDM4E (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14280398 | 0.69 | PGR (0.51) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL30982816 | 0.68 | PSEN1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL31041790 | 0.68 | PSEN1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080020323-A1 | Light sensitive planographic printing plate material | KONICA MINOLTA MEDICAL & GRAPHIC, INC. | 2008-01-24 | — | — | US | disclosed |