Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | APP | P05067 | 3/20 | 0.50 |
| ▸ | VDR | P11473 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280420 | 0.93 | MAPT (0.48) | MAPTAPPVDRL3MBTL1LMNA | |
| SCHEMBL14280425 | 0.91 | MAPT (0.54) | MAPTAPPVDRL3MBTL1LMNA | |
| SCHEMBL14280422 | 0.91 | MAPT (0.52) | MAPTAPPVDRL3MBTL1LMNA | |
| SCHEMBL14280424 | 0.90 | APP (0.38) | MAPTAPPVDRALDH1A1PRSS1 | |
| SCHEMBL14280427 | 0.89 | MAPT (0.50) | MAPTAPPVDRL3MBTL1LMNA | |
| SCHEMBL14280426 | 0.89 | MAPT (0.49) | MAPTAPPVDRL3MBTL1LMNA | |
| SCHEMBL14280440 | 0.88 | CTSL (0.41) | MAPTAPPVDRLMNASMN1; SMN2 | |
| SCHEMBL14280428 | 0.86 | MAPT (0.53) | MAPTAPPVDRL3MBTL1LMNA | |
| SCHEMBL14280439 | 0.84 | MAPT (0.43) | MAPTAPPVDRL3MBTL1LMNA | |
| SCHEMBL14280421 | 0.84 | MAPT (0.51) | MAPTAPPVDRL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7316890-B2 | Indolestyryl compound for use in recording media and method for fabrication thereof | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2008-01-08 | — | — | US | disclosed |