Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280325 | 0.89 | TRPV1 (0.53) | TRPV1CACNA1H | |
| SCHEMBL8209202 | 0.78 | CACNA1H (0.54) | TRPV1CACNA1H | |
| SCHEMBL14265956 | 0.78 | TRPV1 (0.41) | TRPV1CACNA1H | |
| SCHEMBL14280511 | 0.75 | TRPV1 (0.52) | TRPV1CACNA1H | |
| SCHEMBL8201876 | 0.75 | CACNA1H (0.51) | TRPV1CACNA1H | |
| SCHEMBL8217835 | 0.73 | TRPV1 (0.55) | TRPV1 | |
| SCHEMBL8217839 | 0.71 | CACNA1H (0.49) | TRPV1CACNA1H | |
| SCHEMBL8212614 | 0.70 | TP53 (0.55) | TRPV1CACNA1H | |
| SCHEMBL14265957 | 0.69 | TRPV1 (0.59) | TRPV1CACNA1H | |
| SCHEMBL8210251 | 0.68 | TRPV1 (0.62) | TRPV1CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033431-A1 | SPIROCYCLIC AZETIDINONE DERIVATIVES FOR THE TREATMENT OF DISORDERS OF LIPID METABOLISM, PAIN, DIABETES AND OTHER DISORDERS | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |