Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4855162 | 0.87 | PIK3CD (0.40) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL14158805 | 0.84 | MAPK1 (0.46) | MAPTALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL4852894 | 0.83 | NOTUM (0.39) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL4850875 | 0.82 | MAPT (0.38) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL4848229 | 0.79 | MAPT (0.34) | MAPTALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL4848223 | 0.78 | RXFP1 (0.39) | MAPTLMNAMAPK1HTTPDE4B | |
| SCHEMBL14158831 | 0.76 | MAPT (0.55) | MAPTLMNARXFP1MEN1KMT2A | |
| SCHEMBL4856292 | 0.75 | MAPT (0.38) | MAPTLMNASMN1; SMN2MAPK1RXFP1 | |
| SCHEMBL4855863 | 0.69 | RXFP1 (0.36) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL4854091 | 0.69 | ALDH1A1 (0.40) | MAPTALDH1A1LMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7319102-B1 | Pyrrolo[2,3-d]pyrimidine cytokine inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-15 | — | — | US | disclosed |