SCHEMBL14280533

SCHEMBL14280533

Cc1ccc(Oc2ccc(Oc3ccc(-c4ccc(Oc5cccc(Oc6ccc(C)cc6)c5)cc4)cc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.56
TDP1 Q9NUW8 2/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
ALDH1A1 P00352 3/20 0.55
FFAR4 Q5NUL3 1/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
MAPT P10636 2/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
MITF O75030 1/20 0.54
GAA P10253 1/20 0.54
GFER P55789 1/20 0.54
NLRP1 Q9C000 1/20 0.54
NOD2 Q9HC29 1/20 0.54
TEAD4 Q15561 1/20 0.50
POLB P06746 1/20 0.48
ACACB O00763 2/20 0.46
ACACA Q13085 1/20 0.46
FURIN P09958 2/20 0.46
F2 P00734 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL83816 0.93 TDP1 (0.61) HTTTDP1L3MBTL1ALDH1A1FFAR4
SCHEMBL12736461 0.92 SMN1; SMN2 (0.62) HTTTDP1L3MBTL1ALDH1A1FFAR4
SCHEMBL16938819 0.92 HTT (0.67) HTTTDP1L3MBTL1ALDH1A1FFAR4
SCHEMBL15085780 0.89 SMN1; SMN2 (0.60) HTTTDP1L3MBTL1ALDH1A1FFAR4
SCHEMBL10036476 0.87 ALDH1A1 (0.71) HTTTDP1L3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL675770 0.87 ALDH1A1 (0.71) HTTTDP1L3MBTL1ALDH1A1FFAR4
SCHEMBL13026669 0.87 FFAR4 (0.57) HTTTDP1L3MBTL1ALDH1A1FFAR4
SCHEMBL12071804 0.87 FFAR4 (0.57) HTTTDP1L3MBTL1ALDH1A1FFAR4
SCHEMBL12071806 0.87 FFAR4 (0.58) HTTTDP1L3MBTL1ALDH1A1FFAR4
SCHEMBL24322042 0.86 HTT (0.62) HTTTDP1ALDH1A1FFAR4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7317110-B2 Low dielectric constant organo-soluble polyimides HOME SUN INDUSTRIAL CO., LTD. (TW) 2008-01-08 US disclosed
US-7317110-B2 Low dielectric constant organo-soluble polyimides HOME SUN INDUSTRIAL CO., LTD. (TW) 2008-01-08 US disclosed