SCHEMBL14280596

SCHEMBL14280596

C=CC(=O)OCCCCCCOC(=O)Oc1ccc(C(=O)Oc2ccc(C(=O)Oc3ccc(OC(=O)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.48
TDP1 Q9NUW8 3/20 0.48
ALDH1A1 P00352 5/20 0.47
TSHR P16473 2/20 0.47
CYP3A4 P08684 1/20 0.47
PARP10 Q53GL7 1/20 0.47
KMT2A Q03164 8/20 0.46
MAPT P10636 7/20 0.46
MEN1 O00255 4/20 0.46
HPGD P15428 4/20 0.46
RAB9A P51151 1/20 0.43
HTT P42858 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PKM P14618 1/20 0.42
KDM4E B2RXH2 2/20 0.41
HSP90AA1 P07900 2/20 0.41
LMNA P02545 1/20 0.41
LSS P48449 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14072872 0.95 TSHR (0.53) THRBALDH1A1TSHRCYP3A4KMT2A
SCHEMBL816913 0.95 TSHR (0.53) THRBALDH1A1TSHRCYP3A4KMT2A
SCHEMBL14000707 0.95 TSHR (0.53) THRBALDH1A1TSHRCYP3A4KMT2A
SCHEMBL13109517 0.95 TSHR (0.53) THRBALDH1A1TSHRCYP3A4KMT2A
SCHEMBL13656970 0.95 TSHR (0.53) THRBALDH1A1TSHRCYP3A4KMT2A
SCHEMBL14000690 0.95 TSHR (0.53) THRBALDH1A1TSHRCYP3A4KMT2A
SCHEMBL14000687 0.94 TSHR (0.51) THRBALDH1A1TSHRCYP3A4KMT2A
SCHEMBL16885064 0.94 TSHR (0.50) THRBTDP1ALDH1A1TSHRCYP3A4
SCHEMBL10078016 0.94 TSHR (0.50) THRBTDP1ALDH1A1TSHRCYP3A4
SCHEMBL13917592 0.94 TSHR (0.50) THRBTDP1ALDH1A1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080024700-A1 LIQUID CRYSTAL PANEL AND LIQUID CRYSTAL DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2008-01-31 US disclosed
US-20080024700-A1 LIQUID CRYSTAL PANEL AND LIQUID CRYSTAL DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2008-01-31 US disclosed
US-20070139773-A1 Method of producing elliptically polarizing plate and image display using the elliptically polarizing plate NITTO DENKO CORPORATION (JP) 2007-06-21 US disclosed
US-20070139773-A1 Method of producing elliptically polarizing plate and image display using the elliptically polarizing plate NITTO DENKO CORPORATION (JP) 2007-06-21 US disclosed