Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SCNN1A | P37088 | 7/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | GLA | P06280 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293251 | 0.86 | SCNN1A (0.42) | MAPK1SCNN1AGRM5ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL10334226 | 0.85 | SCNN1A (0.41) | MAPK1SCNN1AGRM5ALDH1A1KDM4E | |
| SCHEMBL16541800 | 0.83 | SCNN1A (0.53) | SCNN1AGRM5ALDH1A1KDM4EHPGD | |
| SCHEMBL2287885 | 0.83 | SCNN1A (0.41) | SCNN1AGRM5ALDH1A1KDM4EHPGD | |
| SCHEMBL10461270 | 0.83 | SCNN1A (0.43) | SCNN1AGRM5ALDH1A1KDM4EHPGD | |
| SCHEMBL10462647 | 0.82 | MEN1 (0.44) | SCNN1AGRM5ALDH1A1KDM4EHPGD | |
| SCHEMBL1441745 | 0.82 | SCNN1A (0.48) | SCNN1AGRM5ALDH1A1KDM4EHPGD | |
| SCHEMBL1429031 | 0.81 | SCNN1A (0.50) | MAPK1SCNN1AGRM5ALDH1A1KDM4E | |
| SCHEMBL1428384 | 0.81 | SCNN1A (0.39) | SCNN1AGRM5ALDH1A1KDM4EHPGD | |
| SCHEMBL10461276 | 0.81 | SCNN1A (0.41) | SCNN1AGRM5ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201625-A1 | Organic Comopunds | NOVARTIS AG (CH) | 2011-08-18 | — | — | US | disclosed |
| EP-2300010-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2011-03-30 | — | — | EP | disclosed |
| WO-2011028740-A1 | ENaC BLOCKERS | GLAXO GROUP LIMITED (GB) | 2011-03-10 | — | — | WO | disclosed |
| WO-2011028740-A1 | ENaC BLOCKERS | GLAXO GROUP LIMITED (GB) | 2011-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201625-A1 | Organic Comopunds | OR10J3, CFTR, CLIC1 | MAPK1 3731/4885SCNN1A 52/4885GRM5 3109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.