Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280658 | 1.00 | ADRB2 (0.35) | ADRB2ADRB1ADRB3PTPN2PTPN1 | |
| SCHEMBL14280667 | 0.87 | PTPN2 (0.33) | ADRB2ADRB1ADRB3PTPN2PTPN1 | |
| SCHEMBL14280661 | 0.86 | — | — | |
| SCHEMBL14280669 | 0.86 | — | — | |
| SCHEMBL14280646 | 0.85 | — | — | |
| SCHEMBL14280652 | 0.83 | HTT (0.37) | ADRB2ADRB1ADRB3MEN1LMNA | |
| SCHEMBL14280641 | 0.83 | HTT (0.37) | ADRB2ADRB1ADRB3MEN1LMNA | |
| SCHEMBL14280623 | 0.81 | TSHR (0.42) | PTPN2PTPN1PTPN6 | |
| SCHEMBL14280670 | 0.77 | MEN1 (0.41) | ADRB2ADRB1ADRB3MEN1LMNA | |
| SCHEMBL14280665 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021185-A1 | initiator systems; block polymers of vinyl acetate, vinyl alcohol, or polyvinyl butyral; use as water-soluble films, biodegradable and water-soluble polymers, detergents, in adhesives and as emulsifier; e.g. star polyethylene glycol modified with polyvinyl alcohol groups through a phenylene spacer | CELANESE VENTURES GMBH (DE) | 2008-01-24 | — | — | US | disclosed |